Anosmia and ageusia are the first and maybe the only symptom in patients affected with COVID-19 especially if the patient is paucisymptomatic. This aim of this study was to determine the demographic details of patients with anosmia, prevalence of anosmia and the time taken for it to resolve in patients who are positive for COVID-19 and took treatment in our hospital. Cross Sectional Study. Patients with real time polymerase chain reaction (RTPCR) positive nasopharyngeal and oropharyngeal swabs, who met the inclusion and exclusion criteria were included in the study. The study group was interviewed through telephonic calls and a questionnaire filled to see the development and regression of their symptoms. Of the study population of 1000, 742 patients had some sort of a smell disturbance. There was a positive correlation between the severity of the disease and history of smoking. The prevalence of smell disturbances among COVID-19 patients in our study was 74.2%. One important finding that we found out was that majority of the smokers had moderate disease. Most of the patients had complete recovery form smell disturbance in the due course of time. The mean time for resolution of smell disturbance was found to be 9.89 days. Anosmia and ageusia can represent the only symptomatology present in patients with COVID-19 and they are completely reversible and hence they can be used as early predictors of infection.
Level of Evidence: Level 2.
Background:The relationship between frontal cells to frontal sinus disease pathology remains an understudied area. Caucasian population were studied in most previous studies of the pneumatization pattern of the frontal recess, whereas there are very few reports on the prevalence of frontal recess cells and their relation with frontal sinusitis in India. The purpose of this review is to determine the frequency of occurrence of frontal cells and to determine whether the size of the frontal isthmus or the presence of frontal cells is related to the presence of frontal sinus disease in various articles. There are a lot of studies that appear in the Western literature, but there are less Indian studies on this subject. Materials and methods: In this article, we reviewed around 25 various randomized, clinical, and experimental trials conducted between 1940 and 2016 and which were published in various Indian and American journals. The literature search was conducted after using the key words chronic rhino-sinusitis, Kuhn frontal cells, frontal recess, frontal sinusitis, functional endoscopic sinus surgery, and computed tomography from Pubmed, Cochrane, Proquest, and Google Scholar.
Conclusion:There was no significant relation between any particular frontal recess cell and the size of the nasofrontal isthmus as the cause for frontal sinusitis in majority of studies, and therefore we concluded that various factors, along with the pattern of pneumatization and mucosal edema, contributed to the pathogenesis of chronic frontal sinusitis.
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