2hrs old female, delivered at 38 weeks of gestation with abdominal distension with antenatal Ultrasound suggestive of 12*6 cm cystic mass in lower abdomen, mild hydronephrosis, Bilateral Renal pyelectesis. On examination she had lower abdominal distension, vulval oedema, lower limb oedema and also all four limb polydactyly. Post-natal Ultrasound examination revealed the presence of hypoechoic and corpusculated 12*6 cm cystic lesion in the midline with thick wall in continuity with vagina suggestive of Large hydrometracolpos with bilateral mild hydronephrosis, both ovaries not visualised. Hysteroscopic examination showed obstruction due to imporforated hymen and narrowing at level of cervix and very thick mucoid secretion was found and drainage of about 100ml milky thick mucoid collection under USG guidance was done. 2DEcho was normal. According to these physical features, baby is likely to have McKusick-Kaufman syndrome.

Anaemia is a major global health problem; it results in significant morbidity and mortality among children 85 children below 12 years having anaemia were studied. Complete blood count was done to determine PCV, MCV, MCH, MCHC, RDW, Hb %, along with Peripheral smear (PS) study, Reticulocyte count and Serum iron (Fe), Serum B and Folic acid levels were done Types of anaemia were 50(58.8%) Iron deficiency anaemia, 12(14.1%) Thalassemia, 8 (9.41%) Megaloblastic anaemia, 7(8.23%) Anaemia of acute haemorrhage, 5 (5.88%) Sickle cell anaemia, 2(2.35%) Aplastic anaemia, 1(1.17%) Leukemia. The clinical manifestations were 85 (100%) pallor, 71(83.5%) weakness and fatigability, 32(37.6%) fever, 23(27.05%) 17(20%) shortness of breath, 15(17.6%) hepatomegaly, 12(14.1%) cough, 11(12.9%) history of pica, 11 (12.9%) spleenomegaly, 9(10.5%) petechiae, 8(9.4%) Nausea/vomiting, 8(9.4%) koilonychia, 4(4.7%) hyper pigmentation, 5(5.8%) tremors. Out of the total number of patients screened 18(21.1%) had mild, 39(45.8%) moderate and 28(32.9%) had severe anaemia. The present study of anaemia had Iron deficiency as the major cause followed by Thalassemia, Megaloblastic anaemia, acute Haemorrhage, Sickle cell anaemia and Aplastic anaemia. This study will be helpful to paediatricians to treat such patients efficiently to avoid morbidity and mortality.

Proper feeding practices during first two years of life are essential for the growth and development of young children to prevent malnutrition associated morbidity and mortality. The children aged between 6 months to 18 months were selected for study. The detailed history was obtained from their mother. The different feeding patterns prelacteal feeding, time of inception of first feeding, causes of stoppage of breast feeding studied and classified with percentage.In the study of inception of first feeding 35(46.6%) were < 6hrs, 21 (28%) were 7-12hrs, 10 (13.3%) were 12 to 24hrs, 7(9.33%) were between 25 -48hrs, 2(2.66%) were between 49 – 72 hours. In the study of pre lacteal feeding 16(21.3%) were given honey, 36(48%) sugar solution (water added sugar), 15(20%) plain water, 8(10.6%) milk. The reason for stoppage of breast feeding, 22(29.3%) due to insufficient breast milk, 16(21.3%) maternal sickness, 15(20%) infant sickness, 14(18.6%) maternal employment, 8(10.6%) subsequent pregnancy.: The present study will be helpful to paediatrician to evaluate the feeding pattern to prevent malnutrition, morbidity and mortality in children.

Aims & Objectives: To determine the effectiveness and safety of IV Iron sucrose therapy in antenatal women with moderate to severe Iron deficiency anaemia. Methodology: It is a retrospective study with secondary data analysis. We have analyzed the data collected from January 2019 to December 2019 at the Nootan general hospital, Visnagar, Gujarat, India. Analysis of antenatal  women with moderate to severe anaemia (Hb 6 to 8gm%) in the second trimester  and early third trimester(20 to 34weeks of gestation) are done during their  routine antenatal care  who were prescribed Intravenous Iron sucrose in a standard-dose of 1000 mg given as 200 mg on alternate days after confirming the iron deficiency anaemia. Effectiveness of the therapy has been studied by comparing the Hb level at the point baseline where start of the treatment and 4 week or more after the last treatment was given (endline). The safety profile of the therapy has been assessed by noticing any adverse drug reaction after starting the infusion. Results: Mean increase in Hb in cases of moderate & severe anaemia was 3.69 g/dl (1.19) and 3.91 (1.25) g/dl respectively. Overall rise of Haemoglobin was 3.79 g/dl (1.1)(95% CL: 3.35, 4.23).  Calculated p value in our study is < 0.001 which is statistically significant. Conclusion: The mean rise in Haemoglobin level in our study was 3.79 g/dL when 1000 mg of Intra venous iron sucrose was given to antenatal women with moderate as well as severe anaemia is concerned. The magnitude of the anaemia difference is directly proportional rise of haemoglobin level. The amount of haemoglobin rise is seen more in severe anaemic antenatal patients compared with moderate antenatal patients. We recommend that Intravenous iron sucrose therapy should be included as second choice for severely anaemic pregnant women where situation is not supportive for blood transfusion or patient is noncompliant.

: Neonatal bacterial infection remains a significant cause of neonatal morbidity and mortality. CRP parameter can be the indicator to use the proper antibiotic with certain duration. 60 Neonates &#60; 28 days having/suspicious of bacterial infection (septicaemia) were studied. Blood and Urine culture and sensitivity, routine blood examination, chest x-ray, CRP (serum), were studied. Neonates were classified as per the levels of CRP levels &#60;6 as group 1&&#62; 6 as group 2.Clinical features: 48(80%) born by vaginal delivery, 4(66%) had maternal fever &#62;100.4 F, 6(10%) PROM, 23(38.3%) refusal to feeds, 20(33.3%) were lethargic, 12(20%) had poor cry, 7(11.6%) had jaundice, 8(13.3%) had conjunctivitis, 7(11.6%) had vomiting, 4(6.6%) had excessive cry, 3(5%) abdominal distension, 3(5%) hypothermia, 1(1.6%) had fever, 2(3.3%) diarrhoea, 1(1.6%) umbilical Sepsis. The Gram Negative organismsseen in 20(33.3%). In Group A-28 neonates had CRP value &#60;6 and duration of therapy was &#60;3 days. In group B-32 neonates had CRP value &#62;6, 2 neonates treated for 5 days, 17 for 7 days, 13 for 11 days and 26 neonates had positive blood culture. CRP levels plays vital role to evaluate the duration of antibiotic therapy in neonates of suspected bacterial infection.