Objective: Immunity-related issues are the main concerns of patients undergoing inflammatory bowel disease (IBD) treatment. The treatment of IBD during the last decade has evolved due to the ever-increasing utilization of immunomodulators, which has caused the potential of contracting opportunistic infections to become the main immunity concern for patients affected by IBD. Methods: Studies on opportunistic infections in patients with IBD that were identified in databases such as Google Scholar, PubMed, and Scopus were reviewed and included. Results: IBD patients are a high-risk population for opportunistic infections, with age being a significant factor. The primary therapy for IBD patients includes the suppression of the immunity system, together with immunodeficiency and biological treatments, which, first of all, must be standardized. Since treatment with suppressive medicine, which is the original method for curing IBD, causes viral infections and the growth of various bacteria, factors suppressing the body's immunity system must be temporarily suspended, or the consumption dosage of sensitive antibiotics should be reduced. Biological treatment and anti-integrin antibodies will lead to the danger of being affected by opportunistic infections in patients with IBD. Still, the threat of these infections is not severe. Conclusion: The worldwide research society must conduct further research into a therapeutic strategy for IBD patients to reduce susceptibility and the risk of opportunistic infection.There are still unknowns about how these individuals and the medicines they were given reacted to different infections, and more detailed clinical observations are required.

Background: Fatty acid is a type of carboxylic acid with carbon chain that can be short (4 carbons, such as butyric acid) or long (14 carbons and more, like DHA). Generally, fatty acids are divided into two groups of unsaturated fatty acids and saturated fatty acids. They have important and valuable medicinal properties especially against microbial pathogens. Objective: Studies have shown that the epidemic of the twentieth century's heart disease is due to the abuse of trans fatty acids. The consumption of various fatty acids has various therapeutic effects on various diseases. Method: Relevant articles were searched from Google Scholar, Pub Med, Scopus, Science direct, and Cochrane library. Results: Getting omega-3 fatty acids through diet and supplements affects both acute and chronic inflammation. Consumption of omega-3 fatty acids can slow down the growth of cancer, increase the effect of chemotherapy and reduce the side effects of chemotherapy or cancer. This can be done by reducing angiogenesis in the tumor, creating the differentiation of cancer cells, reducing the risk of heart attack from cancer, etc. Conclusion: In general, fatty acids are valuable and affordable, and available with numerous medicinal properties, including anti-fungal and anti-bacterial properties that can be extracted from and used by many sources, especially many medicinal plants. Since antimicrobial chemicals generally have many side effects and have resistance to many microbial species, various studies and experiments to identify and extract fatty acids and their application to the title of the pharmaceutical formulation are essential.