Currently, the demand for more reliable drug screening devices has made scientists and researchers develop novel potential approaches to offer an alternative to animal studies. Organ‐on‐chips are newly emerged platforms for drug screening and disease metabolism investigation. These microfluidic devices attempt to recapitulate the physiological and biological properties of different organs and tissues using human‐derived cells. Recently, the synergistic combination of additive manufacturing and microfluidics has shown a promising impact on improving a wide array of biological models. In this review, different methods are classified using bioprinting to achieve the relevant biomimetic models in organ‐on‐chips, boosting the efficiency of these devices to produce more reliable data for drug investigations. In addition to the tissue models, the influence of additive manufacturing on microfluidic chip fabrication is discussed, and their biomedical applications are reviewed.
Metal
halide perovskite nanoparticles have recently attracted immense
interest for photodetectors due to their outstanding optical and electronic
properties such as high carrier diffusion length, tunable band gap
(light absorption range), and high photoluminescence (PL) efficiency.
Although significant progress has been achieved in the development
of perovskites, their stability is yet to be addressed. To improve
the stability and quantum efficiency of FAPbI3 perovskite
nanocrystals, we present a room temperature protocol to fabricate
fully passivated and stable FAPbI3 nanocrystals via 2D
growth in the presence of amine ligands and an excess amount of the
organic cations. The crystallization mechanism of 2D colloidal quantum
wells (QWs) with long-time stability is ascribed to the excess amount
of large organic cations which isolate the inorganic lattice octahedral
layers. It is demonstrated that the QW films (130 nm) hold 90% of
their PL intensity after 30 days, which is ∼8 times more stable
than FAPbI3 quantum dot (QD) films. We also show the enhanced
photoresponsivity of QW photodetectors (up to 100%) as compared with
QD devices. The long-term ambient performance of perovskite QW photodetectors
on account of their hydrophobicity is demonstrated. The findings can
shed light on a way to develop ambient stable QW nanoparticle perovskite
optoelectronic devices.
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