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Introduction: Vitiligo is a common depigmenting disorder with profound stigma. Prevalence of vitiligo is 0.5% to 1%. Information about association of progressive vitiligo are well known. Prognostic factors of vitiligo also enlisted. However, little information is available on the risk factors for developing extensive vitiligo. Aims and Objectives: Aims of the study was to identify-factors which are associated with extensive vitiligo (involving more than 5% of the body surface area). The following risk factors were evaluated, Onset before 20 years of age, Duration of disease greater than 2 years, Presence of Koebner's phenomenon, Family history of vitiligo, Presence of leucotrichia and Mucosal involvement. Materials and Methods: A case control study were designed. Patients with Vitiligo > 5% body surface area involvement were classified as cases and <5% body surface area were labeled as controls. The frequency of evaluating associated clinical factors among the cases and controls were used to evaluate the extensive vitiligo's association with risk factors (disease risk associated exposure). Results: Two hundred and eleven patients were evaluated. The mean age at onset was 19.07+13.51 (+SD) years. Acrofacial vitiligo was the commonest type of vitiligo. Duration of disease more than 2 years, presence of Koebner's Phenomenon, Family history, Symmetry of lesions, milky white colour of lesion, presence of Leucotrichia, mucosal involvement and Acrofacial type vitiligo had statistically significant (p<.05) association with extensive vitiligo. Ratio of the odds of the outcomes in two groups was noted significant with Duration of disease more than 2 years, Koebner,s Phenomenon, Mucosal involvement and Leucotrichia. Conclusion: This case-control study has demonstrated a weak association between extensive vitiligo and duration of disease greater than 2 years. It has also indicated that koebner's phenomenon, mucosal involvement and leucotrichia are additional risk factors.

Background: A huge number of patients in our country are affected by Tinea Corporis (TC). The number of patients affected by dermatophytosis has increased by a large extent in the last 4 to 5 years. The quality of life in TC patients can be affected by various factors including the disease morbidity, duration of disease, social & demographic factors. Aims and Objectives: The aim of the study is to find out the effect of TC on the quality of life of the affected patients & along with that to assess whether there is some association of this effect on quality of life with some demographic & clinical factors. Methods: The effect on quality of life of 328 patients affected by TC who attended the Dermatology outpatient's department of NRS Medical College was assessed using the Dermatology Life Quality Index (DLQI) questionnaire. Results: 12 (3.658%) of the patients had an extremely large effect on quality of life. There was a very large effect on the QOL of 121 (36.890%) patients. There was moderate effect on 134 (40.853 %) of the patients. There was a small effect on 59 (17.987 %) of the patients. 2 (0.609 %) patients had no effect on their QOL. Duration of disease & body surface area involved have significant impacts on QOL. Conclusion: The quality of life is adversely affected by TC. Early detection & treatment of the disease is very important. Steps must be taken to increase awareness about the disease among the general population.

BACKGROUND Acne vulgaris is a common disease mostly affecting the adolescents. The lesions can be distributed over the sebaceous rich areas of the body like face, chest, back and upper arm. The commonest location is face. Face is psychologically the most important part of the body. So, the presence of lesions on the face can have significant effects on the quality of life of the patients. The purpose of this study was to assess the effect on the quality of life (QOL) of the patients who have acne vulgaris on their face. Along with that this study was planned to assess as to whether the effect on QOL is related to two demographic factors - age & gender and two clinical factors - duration of disease and grade of acne vulgaris. METHODS 81 patients having acne vulgaris on their face who attended the Dermatology OPD were assessed using the Dermatology Life Quality Index (DLQI) questionnaire. RESULTS Acne vulgaris of the face had significant adverse effect on the QOL of the affected patients. DLQI score was found to be more with increase in age of the patients. There was no significant association between DLQI score & gender. The clinical factors, duration of disease and the grade of acne vulgaris had statistically significant positive correlation with DLQI score. CONCLUSIONS Acne vulgaris had an adverse effect on the QOL of the patients. QOL was more affected with increase in age of the patients. Duration of the lesions and grade of acne vulgaris had a positive correlation with the effect on the QOL of the patients. The lesions can be controlled with treatment. Proper counselling is also very important. KEYWORDS Acne Vulgaris, Quality of Life (QOL), Dermatology Life Quality Index (DLQI)