BACKGROUNDIn postmenopausal women, risk of uterine cervical dysplasia and malignancy is increased, especially in those with no history of previous Papanicolaou (Pap) smears. Therefore, routine screening can help in reducing morbidity and mortality. AIMTo study the uterine cervical cytomorphology in symptomatic postmenopausal women, prevalence of dysplasia/malignancy, to observe the relation of cervical cytomorphology with urogenital symptoms, age of onset and duration of menopause. MATERIALS AND METHODSA total of 102 symptomatic postmenopausal patients underwent Pap smear examination and reporting was done based on The 2001 Bethesda System. RESULTSOut of 102 smears, 101(99.02%) cases were satisfactory for reporting. Age ranged from 44 to 79 years with mean and median age of 54.3±6.8 and 52.5 years respectively. Maximum cases were in the 50-59 age group, 57(56.5%) cases. Age of onset of menopause varied from 40 to 56 years with mean and median age of 48.6±3.4 and 49 years respectively. Duration of menopause ranged from 1 to 26 years with mean and median duration of 5.78±5.7 and 4.0 years respectively. Negative for intraepithelial lesion or malignancy (NILM) and epithelial cell abnormalities (ECA) were 86(85.1%) and 15(14.9%) cases respectively. ECA were most commonly seen in the 60-69 years' age group, 7(46.7%) cases. Overall prevalence of cervical dysplasia was 9(8.9%), with highest prevalence in the 60-69 age group, 5(27.7%); and carcinoma was 3(2.9%) with highest in the 60-69 age group, 2(11.1%) cases. Vaginal discharge was the commonest urogenital symptom, 40 (39.8%) cases. Reactive cellular changes (RCC) was the commonest finding in vaginal discharge, 24(60%) cases. Maximum cases of ECA, 12(44.4%) cases, were associated with postmenopausal bleeding (PMB). Mean age in dysplasia and malignancy (58.6±7.3 years) was significantly higher (P<0.019), with higher proportion in women >54 years (P<0.030). Significant correlation of dysplasia and malignancy was seen with duration >5 years (P<0.011). CONCLUSIONPap smear examination in symptomatic postmenopausal women will definitely bring about better management of cases thereby improving the quality of life. KEYWORDSPap smear, Postmenopausal women, Cervical dysplasia, HPV, Cervical cancer. HOW TO CITE THIS ARTICLE: Kaiho N, Devi LS, Singh LR. Uterine cervical cytomorphology in symptomatic postmenopausal women.

Association of systemic lupus erythromatosus with hemophagocytic lymphohistiocytosis (HLH) has been reported by many authors 1,2,3,4 however association of systemic lupus erythromatosus with hemophagocytic lymphohistiocytosis and hypoplastic bone marrow is quite rare. Here we are reporting a case of HLH developing in a known case of SLE presenting with hypoplastic bone marrow in a 45 years old female, on low dose steroid therapy who presented with febrile pancytopenia, hepatosplenomegaly, hyperferritinemia with evidence of bone marrow hypoplasia and haemophagocytosis.

Hidradenoma papilliferum is a rare, benign adnexal tumor considered to be of apocrine origin that occurs almost exclusively in females on the anogenital area. Ectopic or non-anogenital hidradenoma papilliferum is rare. But ectopic hidradenoma papilliferum associated with pilomatricoma has not been described in literature to our knowledge. We describe a case of hidradenoma papilliferum associated with pilomatricoma presenting with an intradermal nodule, 1cm in diameter on the right side of the back of the neck with history of 15 years duration. This case is reported because of its rarity.

ABSTRACT:Respiratory epithelial adenomatoid hamartoma (REAH) is a rare benign lesion of the upper aerodigestive tract seen mainly in adult males. The lesion usually occurs in the nasal cavity though other locations have also been described. Recognition and awareness of this lesion is necessary as it may be confused with more aggressive lesions which require a significantly different treatment approach. A complete surgical resection is curative for REAH. We report a case of REAH in an adult male presenting with a mass in the nasal cavity. This case is reported because of its rarity and the potential risk of misdiagnosis.

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