Background: Uterine mesenchymal tumours are a heterogeneous group of neoplasms that can frequently be diagnostically challenging. Most subtypes of leiomyoma are chiefly of interest in that they mimic malignancy in one or more respects. Objective: To evaluate the histomorphological features of uterine leiomyomas and its variants. Materials and methods: Total of 477 cases of uterine leiomyomas and its variants were analysed prospectively in a period of 2years during July 2010 to June 2012 to assess the various pattern of leiomyomas. Cases were studied in detail about complete history, clinical examination and other findings. Results: In the study 468 (98.11%) cases showed features of conventional leiomyoma and 8 cases showed variants of leiomyomas (1.68%). Conclusion: Although their diagnosis is straight forward in most cases, difficulties arise with particular leiomyoma variants, especially highly cellular leiomyoma (often confused with an endometrial stromal tumour) and leiomyoma with bizarre nuclei, mitotically active leiomyoma which may cause concern for leiomyosarcoma.
Soft-tissue sarcomas (STSs) are rare neoplasms that can be initially evaluated by fine-needle aspiration cytology (FNAC). Although they are difficult to subtype, these sarcomas can be graded and classified based on cytomorphology. FNAC, with clinical and radiological correlation, can be effectively used in the diagnosis of STSs. Application of ancillary techniques is essential to arrive at the final diagnosis. The aim of the study was to determine the efficacy of FNAC in the initial diagnosis of STSs. Three patients who presented with soft-tissue masses were initially evaluated by ultrasound and/or magnetic resonance imaging and FNAC. Following which, all the three cases were operated on and studied on histopathology and immunohistochemistry to arrive at a final diagnosis. All the three cases were diagnosed as malignant on FNAC even when radiology findings differed or was not confirmatory in one case. FNAC diagnosis was appropriate in case of grading of tumors and classification based on morphology in all the three cases. FNAC of soft-tissue tumors (STTs) is a quick, reliable, and cost-effective mode of initial investigation for STTs. Although it is difficult to subtype the diagnosis, in majority of the cases, a diagnosis of benign or malignant and grade of the tumor can be assessed.
Background: Handouts make the lectures "portable and enduring". Students' performance, can vary depending on the type of handouts. Complete handouts are one which contains 100% content of the lecture and incomplete hand-outs are one which contains 75% of the lecture content. Note-taking by students is generally seen as an integral part of the process of learning from lectures. But it interferes with ability to listen. Writing in the blank spaces in hand-out during a lecture may not interfere with listening ability and allow students to be alert and active, and learn by writing. Objectives: To asses and to know the perception of 2 nd year MBBS student on the usefulness of incomplete handouts over complete handouts in pathology lectures. Methodology: It is an intervention study done in 41 students of 2nd MBBS in pathology lectures, where the complete handout given to the students on the day of lecture and after the class a recall test was conducted. After 1week a retention test was conducted. Similar intervention was done for the incomplete handout. Pre validated MCQs was used. The feedback was taken at the end of the study. Results: study showed the results in MCQ scores for incomplete handout (mean=5.73+1.24) is better than complete handout MCQ scores (mean=3.61+1.51) and the majority of students felt that incomplete handouts increased their motivation in learning and helped in understanding pathology. Conclusion:Majority of student perception towards the use of incomplete handouts was more than the complete handouts. The effectiveness of incomplete handouts is also shown better than complete handoout.
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