Background: Diabetic foot ulcers continue to pose significant global issue despite the advances made in the management of diabetes. It causes major foot complications if they are not addressed properly. It needs multidisciplinary approach for its care. While several advancements has taken place in wound care management, platelet rich plasma and stem cell therapy promises to offer a new hope in its management, aiding in cellular and tissue regeneration. The purpose of the present study was to compare Platelet-Rich Plasma versus conventional dressing in the management of diabetic foot ulcers.Methods: This prospective study was focused on 20 diabetic foot ulcers, carried out in a surgical unit of ACS Medical College and Hospital, Chennai, Tamil Nadu, from January 2018 to June 2018. Patients were divided into two groups; Group A received conventional ordinary dressing (N=10, 50%) and Group B received PRP dressing (N = 10, 50%). The mean follow-up period was 8 weeks.Results: The estimated time of wound healing was 8 weeks and healing was found to be more effective for patients in group B compared to patients in group A; the PRP group was found to be more effective in wound healing with fewer complications, less infection, exudates and pain.Conclusions: There have been considerable advances in the use of PRP in therapeutic processes in recent years in tissue regeneration therapy. PRP is a powerful tool for the treatment of chronic wounds and very promising for diabetic foot wounds; PRP enables healing, and reduces amputation rates, infection and exudates.

Background and Objectives: Gastric cancer remains one of the most common and deadly cancers worldwide. Based on GLOBOCAN 2018 data, stomach cancer is the 5th most common neoplasm and the 3rd most deadly cancer, with an estimated 783,000 deaths in 2018. Gastric cancer incidence and mortality are highly variable by region and highly dependent on diet and Helicobacter pylori infection. Hence the aim of this study was to analyze the benefits of upper gastrointestinal endoscopy (UGI Scopy) among patients with Gastro Esophageal Reflux Disease symptoms (GERD) and analyze the results of the same, in an attempt to find and diagnose patients with early stage gastric cancer. Materials and Methods: A cross-sectional study of all patients attending general surgical outpatient department for dyspepsia, GERD and associated symptoms during the year 2019-2020. After institutional ethical clearance, patients written informed consent was obtained after explaining the procedure to them. A through history and examination was done and following this UGI scopy was performed and the findings recorded. Results: there were a total of 2038 cases. Among these patients 95.78% of them had significant findings. Reflux esophagitis was found in 13.7%, Antral gastritis in 26.4% and Pangastritis in 39.6%, Duodenitis was found in 10.69%, esophageal varices in 4.31% and esophageal candidiasis was 3.72%. 7.2% of the patients were diagnosed with malignancies. Conclusion: Upper GI endoscopy is therefore an effective tool to facilitate earlier diagnosis and treatment in patients with GERD like symptoms.

Background:The aim of the study was to evaluate an association of serum lipid profile in women with benign breast disease and to analyze a possible relationship between serum lipid profile and benign breast diseases with emphasis to laboratory findings. Methods: Hospital based study carried out at ACS Medical College, Chennai, during the period of June 2018 to November 2018. 75 women in General Surgery ward/outpatient were included in the study. Subjects included in the study were women of age between 16 to 35 years, provided they fulfilled inclusion and exclusion criteria. History was noted, serum lipid profile was done. Results were noted and analysed. Results: Out of 75 subjects, 21.3% of women with benign breast disease were having elevated serum lipid profile. Conclusions: It is concluded that benign breast disease is associated with altered serum lipid profile namely hyperlipidemia. Therefore, routine screening and treatment of this condition is must among women with benign breast disease by dietary management, use of anti-hyperlipidemic drugs to achieve long lasting cure and to prevent possible future recurrences.