The challenge of antimicrobial resistance (AMR) is grave in developing countries. Antimicrobials are misused yet stakeholders’ contribution to antimicrobial stewardship is low. Veterinary students are future prescribers and their knowledge could influence progress in combating AMR; hence, there is a need to assess their knowledge, attitude, and awareness of AMR. A multi-institutional questionnaire was administered to undergraduates in Nigerian veterinary schools. It comprised demographics, own personal antibiotic usage, and knowledge, attitude, and awareness of AMR in humans and animals. Descriptive statistics and logistic regression were used for analyses. Of the 426 respondents, 39.2% reported personal antimicrobial use in the previous six months. Over 60% received knowledge scores lower than average and >87% requested more education on clinical use and prescriptions pre-graduation, monitored dispensing of antimicrobials, conducting AMR research, and confirmed link among human, animal, and environmental health. Less than 25% of respondents were aware of antimicrobial stewardship and global efforts/organizations for AMR. Final year students have 9-fold and 14-fold more satisfactory knowledge on antimicrobials in humans and animals compared with other students, respectively (p = 0.001). Final year students also have more knowledge (13×) and awareness of contributory factors (3×) on AMR (p = 0.001) than other students. Unsatisfactory knowledge on AMR issues exists among veterinary students yet willingness to improve was observed. Identified knowledge, attitude, and gaps in AMR awareness should be targeted by veterinary schools in Nigeria.

Antimicrobials are used to maintain good health and productivity of food animals. Misuse of antibiotics in livestock contributes to development of antimicrobial resistance, an emerging One Health issue. This study assessed pastoralists' knowledge and practices regarding antimicrobial usage, explore pathways for resistant pathogens emergence and associated social drivers for antimicrobial misuse in pastoral herds of North-central Nigeria. An interview questionnaire-based cross-sectional survey was conducted in randomly selected pastoral households. Descriptive and analytical statistical analyses were performed at 95% confidence level. All the 384 pastoralists participated in the study. Majority (58%) of respondents had no formal education. Only 8.1% of respondents knew antibiotic misuse to be when given under-dose and 70.1% of them did not know what misuse entailed. About 58.3% reported self-prescription of antimicrobials used on animals, while 67% of them reported arbitrary applications for dosage determination. Most frequently used antimicrobials were tetracycline (96.6%), tylosin (95.6%) and penicillin (94.0%). Identified pathways for antimicrobial resistant pathogens spread to humans were through contaminated animal products; contaminated animals and fomites; and environmental wastes. Improper antimicrobial usage (p < 0.001), non-enforcement of laws regulating antimicrobial usage (p < 0.001), weak financial status (p < 0.001), low education and expertise (p < 0.001), and nomadic culture (p < 0.001), influenced antimicrobials misuse in livestock. The study revealed low levels of knowledge and practices regarding antimicrobial usage in livestock. Socio-cultural activities significantly influenced antimicrobials misuse in livestock. Improve pastoralists' knowledge about effects of antimicrobials misuse and promotion of prudent usage in livestock will mitigate antimicrobial resistance menace in animals and humans.

There is considerable global concern over the emergence of highly pathogenic avian influenza (HPAI) that has affected domestic poultry flocks in Nigeria and other parts of the world. There have been little investigations on the proposition that free-range flocks are potentially at higher risk of HPAI than confined small-scale commercial enterprises. The objective is to analyse the biosecurity measures instituted in the small-scale commercial poultry farms and established free-range bird flocks owned by households in the rural areas and qualitatively assess the risk status at the two levels of poultry management systems in northcentral Nigeria. We used data collected through questionnaire administration to farms and flock owners and subjected them to a traffic light system model to test for relative risks of HPAI infection based on the biosecurity measures put in place at the farm and flock levels. The results indicate that free-range flocks are at lower risk compared to small-scale commercial operations. These findings are plausible as birds from free-range flocks have more opportunities to contact wild bird reservoirs of low-pathogenic avian influenza (LPAI) strains than small-scale commercial poultry, thus providing them with constant challenge and maintenance of flock immunity. The development of efficient and effective biosecurity measures against poultry diseases on small-scale commercial farms requires adequate placement of barriers to provide segregation, cleaning and disinfection, while concerted community-led sanitary measures are required for free-range poultry flocks in the developing topical and subtropical economies.

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