Antimicrobials usage assessments in commercial poultry and local birds in North-central Nigeria: Associated pathways and factors for resistance emergence and spread

Alhaji, Nma Bida; Haruna, A.E.; Muhammad, B.; Lawan, Mohammed Kabiru; Isola, Tajudeen Opeyemi

doi:10.1016/j.prevetmed.2018.04.001

Cited by 44 publications

(39 citation statements)

References 42 publications

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“…Small-scale intensive operations typically raise broiler or layer chickens with antimicrobials administered in commercial feed and water [ 15 , 43 ]. Various studies have reported that inappropriate use of antimicrobial agents remains common among family operated systems due to a lack of AMR awareness and access to quality veterinary services [ 116 , 117 , 118 ]. Intensive family operations typically lack the financial resources to support minimal biosafety standards that are present in commercial operations.…”

Section: Introduction To Poultry Production Systemsmentioning

confidence: 99%

A Review of Antimicrobial Resistance in Poultry Farming within Low-Resource Settings

Hedman

Vasco

Zhang

2020

Animals

149

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The emergence, spread, and persistence of antimicrobial resistance (AMR) remain a pressing global health issue. Animal husbandry, in particular poultry, makes up a substantial portion of the global antimicrobial use. Despite the growing body of research evaluating the AMR within industrial farming systems, there is a gap in understanding the emergence of bacterial resistance originating from poultry within resource-limited environments. As countries continue to transition from low- to middle income countries (LMICs), there will be an increased demand for quality sources of animal protein. Further promotion of intensive poultry farming could address issues of food security, but it may also increase risks of AMR exposure to poultry, other domestic animals, wildlife, and human populations. Given that intensively raised poultry can function as animal reservoirs for AMR, surveillance is needed to evaluate the impacts on humans, other animals, and the environment. Here, we provide a comprehensive review of poultry production within low-resource settings in order to inform future small-scale poultry farming development. Future research is needed in order to understand the full extent of the epidemiology and ecology of AMR in poultry within low-resource settings.

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Section: Introduction To Poultry Production Systemsmentioning

confidence: 99%

A Review of Antimicrobial Resistance in Poultry Farming within Low-Resource Settings

Hedman

Vasco

Zhang

2020

Animals

149

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“…There was an overall Salmonella prevalence of 55% and 23% based on locations and from samples, whereas over 80% of the farmers utilize and abuse antimicrobial drugs as preventive or therapeutic drugs without laboratory diagnostics and veterinary prescriptions. This attitude would accentuate the level of single or multi drug (antimicrobial) resistance situations in the Nigerian broiler industry, especially in situations where compounded drugs and extra-label human drugs are also accessible for use [17,18,19]. It is therefore not surprising that most of the Salmonella isolates obtained in this study were highly resistant to the commonly accessible antimicrobials in the market.…”

Section: Discussionmentioning

confidence: 94%

Antimicrobial Drug Administration and Antimicrobial Resistance of Salmonella Isolates Originating from the Broiler Production Value Chain in Nigeria

et al. 2019

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Salmonella is among the pathogens on the high global priority lists for monitoring for studies on the discovery of new antimicrobials and understanding of how antimicrobial resistance (AMR) develops. AMR in connection with antibiotic usage patterns has been considered as a strong factor and contributor to the AMR pool. The purposes of use, pattern of antimicrobial drug administration, as well as the prevalence of AMR in Salmonella originating from the Nigeria broiler production value chain (NBPVC) was explored. A well-structured questionnaire on antimicrobial usage (n = 181) was used for sampling that focused on 21 antimicrobials from 151 locations. Simultaneously, AMR testing for 18 commonly used antimicrobials on Salmonella in humans was also carried out. Antimicrobial resistance Salmonella spp. were isolated in 23% of the samples (261 of 1135 samples from the broiler input, products, and the environment) using modified ISO 6579 and invA PCR protocols. Over 80% of the antimicrobials used in the NBPVC were administered without a veterinarian prescription. Prevalence of antimicrobial administration without prescription were as follows: live-bird-market (100%), hatchery (86.7%), grow-out-farm (75%), and breeder (66.7%). Widespread prophylactic and metaphylactic use of antimicrobials were recorded with the highest use seen for enrofloxacin (63% and 24%), tetracycline (58% and 33%), and erythromycin (50% and 17%). Antimicrobial resistance was highest for flumequine (100%), penicillin (95%), and perfloxacin (89%). High levels of use without laboratory support of a newer generation of a class of antibiotics suspected to confer high resistance on older generations of the same class (quinolones) was observed.

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“…Beyond above-mentioned drivers, other factors that could be responsible for antimicrobial resistance in meat and meat products include improper dosage of antimicrobials, non-enforcement of laws regulating antimicrobial usage in livestock, weak financial status of livestock farmers, low education and expertise of farmers, and husbandry system (intensive and extensive) [4]. For instance, Alhaji et al [4] in a study found that majority of the poultry famers did not practices or comply with antimicrobial withdrawal periods before slaughter or marketing of their product for consumption. Noncompliance with antimicrobials withdrawal periods could create low therapeutic doses and high concentration of antimicrobial residues in meat products.…”

Section: Other Important Driversmentioning

confidence: 99%

“…According to Zekarias et al [90] difference in disease resistance among individuals and breeds are based on immunological system and its interaction with physiological and environmental factors. Alhaji et al [4] found in their study that antimicrobials are rarely used in local bird flocks, making them likely organic and safe from Veterinary Drug Residues in Meat and Meat Products: Occurrence, Detection and Implications DOI: http://dx.doi.org /10.5772/intechopen.83616 antimicrobial residues and resistance. However, most of the indigenous breed are less productive than some imported or exotic breeds and so do not meet producer's needs.…”

Section: Possible Solution For Eliminating Antimicrobial Residues In mentioning

confidence: 99%

“…These drugs have been used to strengthen profitability and productivity of modern food-animal production by facilitating earlier weaning, higher animal densities, carcass yield and meat quality as well as the use of cheaper feed sources [2]. Among the antimicrobials that are commonly used in livestock production are tetracyclines, amprolium, penicillin, streptomycin, sulphonamides, tylosin, aminoglycosides, β-lactams, macrolides and lincosamides, quinolones, sulfonamides and tetracyclines [3,4] while that of antiparasitic agents include anthelmintics or coccidiostats, stilbenes, amphenicols, nitrofurans, nitroimidazoles, carbamates, pyrethroids and sedatives.…”

Section: Introductionmentioning

confidence: 99%

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Veterinary Drug Residues in Meat and Meat Products: Occurrence, Detection and Implications

Falowo¹,

Akimoladun²

2020

Veterinary Medicine and Pharmaceuticals

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Application of veterinary drugs in livestock production is inevitable as they are essential for treatment of diseases, prevention of diseases, modification of physiological functions, improvement of growth and productivity as well as for ensuring food safety. However, recent reports have revealed that the use of veterinary drugs in large amounts and consistently could result in deposition of antimicrobial residues in muscle and organs of animal. Consumption of these residues in animal products may pose health risk to consumers including development of antibiotic resistance bacteria, allergy, reproductive disorder and hypersensitivity reaction. It is in line with this that this chapter seeks to examine the cause, occurrence, mode of detection, health implication and possible solution to veterinary drugs residues in meat and meat products.

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Antimicrobials usage assessments in commercial poultry and local birds in North-central Nigeria: Associated pathways and factors for resistance emergence and spread

Cited by 44 publications

References 42 publications

A Review of Antimicrobial Resistance in Poultry Farming within Low-Resource Settings

A Review of Antimicrobial Resistance in Poultry Farming within Low-Resource Settings

Antimicrobial Drug Administration and Antimicrobial Resistance of Salmonella Isolates Originating from the Broiler Production Value Chain in Nigeria

Veterinary Drug Residues in Meat and Meat Products: Occurrence, Detection and Implications

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