Objectives:To evaluate the effect of half adult dose of oral Rifampicin on mean change in best corrected visual acuity and central macular thickness in patients with central serous chorioretinopathy.Methods:Thirty-eight eyes of 31 patients with idiopathic central serous chorioretinopathy (CSCR) were registered. Unaided Visual acuity, best corrected visual acuity was documented and detailed slit lamp examination along with dilated ophthalmoscopy was performed. All subjects were treated with oral Rifampicin 300 mg (half adult dose) daily for 03 months. Patients underwent a complete ocular and systemic examination as well as central macular thickness (CMT) measurement by optical coherence tomography (OCT) every month after starting treatment until four months. Fundus fluorescein angiography (FFA) was performed in recurrent cases. Liver function tests were carried out prior to the treatment and during follow up period.Results:A total of 38 eyes of 31 patients (24 males, 07 females) were included in the study. Mean age of patients was 36.16±3.19 years (range 30-44). Mean best corrected visual acuity (BCVA) before treatment was 0.56±0.11 and improved to 0.47±0.14 at 04 weeks (P<0.001) of treatment. The mean CMT at the time of presentation was 494.39±96.29 um and was decreased to 306.90±50.71 um after 04 weeks of treatment (P<0.001). The mean induced reduction in CMT was 187.48±122 um (P<0.001) while that in BCVA 0.41±0.16 at 04 weeks of treatment (P<0.001). Liver function tests were within normal range before and after the treatment.Conclusion:Half adult dose rifampicin (300mg) is effective and safe in treatment of central serous chorioretinopathy without causing any systemic imbalance.

Objectives: To assess the role of lingual flap in encountering lingual nerve injury during the surgical elimination of lower wisdom tooth. Study Design: Cross Sectional Case Control study. Setting: Department of Oral & Maxillofacial Surgery, Institute of Dentistry, Liaquat University of Medical & Health Sciences Jamshoro / Hyderabad. Period: January 2016 to September 2016. Material & Methods: Subjects were categorized into two categories: Group-A (lingual flap) & group-B (control group) each having 52 patients by Lottery method. In group A an envelope mucoperiosteal flap followed by lingual flap elevation carried out and in group B only envelope flap was carried out. All patients were reviewed on the first postoperative day and again 1 and 3rd week after surgery. At each postoperative visit, patient was examined for sensory nerve impairment of the lingual nerve by same observer. Results: Total 104 cases were studied, all the cases categorized among two groups 52 in each group. In group-A 34 were males and 18 were females, while in group-B 44 were male and 8 were females. There was no significant difference among both groups according to the pre-operative assessment. According to objective findings, lingual nerve paresthesia was found among 2 cases of group A on 1st visit, while no any case was found with nerve injury in group B. Out of 2 cases, one case was improved and only one had presented with complain at 2nd visit and 3rd visit, no significant difference among both groups, p-values were quite insignificant. Conclusion: It was concluded that lingual nerve injury (LNI) occurred among few cases of lingual flap group which was insignificantly higher as compare to control group, but the nature of injury was temporary.

Objective: To find out the chemical agents responsible for eye injuries,assess magnitude of the problem and resultant visual outcomes in our dependent population. Design: Observationalstudy. Place and Duration of Study: Eye department, CMH, Hyderabad from Jan 2004 to Dec 2005. Patients andMethods: Thirty five patients of all ages who presented with history of chemical injury to eyes during a period of twoyears were included in this study. Patients with co-morbidity of eyes were not included. Cases were studied to find outcausative chemical agents and their nature, sex distribution, cause and place of the incident, duration of exposure (timeelapsed between chemical injury and copious irrigation at the time of presentation) and effect on visual function.Results: Chemical injuries sustained by 47 eyes of 35 patients were analyzed. All of them were accidental and mostlymales were affected at their workplace. Nearly one third of the times 12(34.29%) both eyes were affected and23(65.71%) cases were unilaterally affected. 30(85.72%) patients presented within first two hours of the injury.3(8.57%) presented within 12 hours and 2(5.72%) presented within 24 hours. Severity of injury was grade I in mosteyes i.e. 37(78.73%) and grade II in 10(21.27%). None was found to have grade III or IV injury. Immediate irrigationwas reported in 29(82.86%) cases. The visual prognosis for eyes that received immediate irrigation was significantlyimproved. 27(77.14%) cases were caused by alkalis and 8(22.86%) were due to acids. 26(74.28%) of the cases weredue to lime. A visual acuity of 6/6 was achieved in 40(85.10%) eyes at follow up after 01 week. 7(14.89%) eyesdeveloped corneal haze of varying degree resulting in BCVA of 6/9 to 6/18. Eye protection was not used in any of the35(100%) cases. 1(2.13%) eye developed cataract during follow up period and needed to be operated upon for visualrehabilitation. Conclusion: All ocular chemical injuries resulted from accidents; at work or at home and none resultedfrom assault. Most of the injured persons needed to be hospitalized on an average for 03 days. Lime was found to bethe major culprit and was found to be used extensively for painting purposes. Visual outcome correlated with severityof injury at initial presentation.

Objective: To compare visual assessment between phacoemulsification and small incision with 5.2mm non-foldable intraocular lens implant. Study Design: Experiential Study. Setting: Institute of Ophthalmology, Liaquat University Hospital Jamshoro, Period: September 2019 to August 2020. Material & Methods: We performed cataract surgeries using the non-foldable intraocular lens in 100 patients. Two techniques were performed, dividing patients equally into Phaco (Group-A) and SI (Group-B) cataract surgery. The outcomes of both were analyzed uncorrected visual acuity and complications. Results: Of the total 50 patients who underwent phacoemulsification, 55% were male and 45% females in Group-A while Group B (SI surgery) were 45% were male and 35% were female. The intra-operative success rate was 90% in Phaco group and 74% in SI group. In comparison, small Incision group had 10% of patients had difficulty in capsulorhexis, 8% in posterior capsular rupture, 6% in zonular dialysis, 2% iridodialysis, and 0% showing nucleus drip with all complications being higher than in Phaco Group except for nucleus drip (2% vs. 0%). Although, post-operatively, individually groups have similar complications with no notable difference seen, yet astigmatism was lesser in Group A than in Group B. Conclusion: Both techniques showed similar outcomes in the uncorrected visual acuity; however, astigmatism and complication rates were lesser in the phacoemulsification study group.