This study aims to examine or analyze the effect of work behavior, integrity and organizational climate on the performance of personnel in the medical and health sector. This research is a quantitative approach. The population in this study was personnel in the medical and health sector with a sample of 51 people. The analysis used multiple linear regression analysis with the help of IBM SPSS 22 Software. The results of the study showed that (1) work behavior had a positive and significant effect on the performance of personnel in the medical and health sector, (2) the integrity of personnel in the medical and health sector, and (3) the organizational climate had a positive and significant effect on the performance of personnel in the medical and health sector. (4) Simultaneously work behavior, integrity and organizational climate have a positive and significant impact on the performance of personnel in the medical and health sector.