Objective: To determine the prevalence of Covid-19 in the district of Gujrat, its association with gender, age, its correlation with respiratory and cardiac symptoms and to find the link of this disease with travel history of patients to affected areas. Methodology: A total of 222 COVID-19 -Positive patients (Male and Female) out of 514 clinically suspected cases (fever, cough, dyspnoea, lethargy & anosmia) as per WHO guidelines were selected. The use of the data for research purposes was explained to patients, and informed consent was taken. The study was approved by the ethical committee of Aziz Bhatti Shaheed Hospital. Samples were extracted from nasopharyngeal swabs using standard extraction protocol. Statistical tools used was SPSS Version 24. Chi-square test and correlation of age with respiratory and cardiac symptoms was calculated. Results: Male gender was significantly affected by this disease (P=0.001) as compared to the female gender. Regarding the prevalence of respiratory symptoms, 31(14%) were asymptomatic. 37(16.7%) had Dyspnea, 45 (65.3%) cough (P= 0.001). Nine (4.1%) developed pneumonia. Fever and Cough was the most common symptom in the age group 21-40 yrs(P=0.001). While pneumonia developed in the older age group. The cardiac symptoms appeared in young age group (p=0.000) in the age group 21-40 yrs (70.9% n=78).38 patients (17.2%) had the symptom of chest pain, 24(10.9%) tachycardia and 1(0.5%) developed arrhythmia. Out of 222 COVID positive patients, 67.1% (149) gave a history of direct contact with positive patients, 19.8% (n=44) gave travel history,4.5% (n=10) had a history of going to Raiwind Ijtamah and 8.6% (n=19) were zaireen/pilgrims from Taftan. Conclusion: The COVID -19 is comparatively more common in male patients. 50% of the patients were of age group 21-40 years showing the symptoms of fever and cough along with mild cardiac symptoms. Acute pneumonia developed in older age groups while cardiac symptoms were significant in young age. In Gujrat District, the majority of the patients (67.1%) developed Covid-19 due to travelling.

IntroductionGlobally rising the number of daily COVID-19 cases has triggered the incredible surge in the information (and misinformation) regarding COVID-19. This misinformation was about numbers of cases, inaccurate guidelines, advertisement of unapproved treatments, and remedies as cures. The increasing prevalence of depression and anxiety was found to be linked directly to the misinformation catered from social media. The study aims to explore the mental health of medical students due to a surge in information and misinformation regarding Covid-19.Materials and MethodsThis cross-sectional study was conducted online from August 2020 to January, 2021. 227 MBBS students of IMDC (1st year to final year with age range 19-25 years) were invited to participate in an online survey through Google docs. Those who were on medication for anxiety and depression were excluded from the study. The use of the data for research purposes was explained and written consent in the first section of the online survey was given to all participants before filling the questionnaire which was divided into 3 sections. The first part was about Demographic information. The second part consisted of 5 questions about info-media use and the third part consisting of 12 questions about mental health including stress-related and behavioral changes, somatic symptoms, emotional disturbance, and cognitive functioning during the covid-19 pandemic. Ethical Approval was taken from the ethical committee of IMDC. A Chi-square test was applied to calculate the significance of qualitative variables and determine the prevalence of mental health.ResultsThe total number of students who participated in this survey were 227 (28.2% males and 71.8% females). Among types of info-media, Whats-app was used most frequently by MBBS students. Different questions were asked regarding Info-media usage and mental health. A significant association was found between gender (Both males and females) and feelings of fear and worry (p-value 0.004**), feeling socially isolated(p= 0.005**), difficulty in communicating with people (p = 0.021*), feeling confused in decision making as time progressed( 0.008**), lack of interest in studying or difficulty in concentration during this time (p 0.037*) and effect on memorizing ability (0.000)**.MBBS students who were regularly using Info-media showed a significant disturbance in mental health problems including stress-related and behavioral changes and somatic symptoms. They were found to be significantly fearful and worried (p-value 0.010*), had difficulty in communicating with people regarding covid-19(p-value 0.021*), and also felt a change in appetite-valuable 0.030*). No serious mental health problem was found related to cognitive functioning. ConclusionIn conclusion, our findings show that there is a high prevalence of mental health problems, which were positively associated with frequent use of info-media during the COVID-19 outbreak.

Background:Studies have shown higher rate of various psychiatric disorders among individuals with substance abuse / dependence. There is little data in developing countries, such as Pakistan, on prevalence of psychiatric co-morbidity in this population and impact on treatment.Objective:To assess the psychiatric co-morbidity among individuals with substance dependence and to determine its demographic associations in patients with substance dependence in Pakistan.Method:This was a descriptive study conducted at a tertiary care hospital in Pakistan. Participants were 588 individuals with substance dependence admitted to a tertiary care hospital in Pakistan, mainly in male inpatient substance dependence unit. The patients were assessed for psychiatric co-morbidity using DSM IV criteria. Informed consent was obtained. The study was approved by the Institutional Research Committee. The results were obtained by using chi square test on SPSS 17.Results:Out of 588, 200 patients (34%) were found co-morbid with other psychiatric disorders along with substance dependence. Reason of first substance use and history of previous substance dependence were observed to be significantly associated with co-morbid psychiatric disorders, x2 (48, n = 549) = 112.396, p < 0.01 and x2 (18, n = 588) = 29.66, p = 0.041 respectively.Conclusion:There was high rate of psychiatric co-morbidity among individuals with substance dependence in this sample.Depression, personality disorders and anxiety disorders were the major co-morbid diagnosis among this population.