Objective: C-reactive protein (CRP) has been implicated as a possible mediator of the association between periodontitis and several systemic diseases. This study evaluated the impact of nonsurgical periodontal treatment on the serum levels of CRP in chronic kidney disease (CKD) patients on hemodialysis. Methods: A total of 77 CKD patients on hemodialysis were included in this study. At baseline, periodontal examination was assessed for all the patients, and chronic periodontitis was defined through clinical attachment level and probing pocket depth, according to the American Association of Periodontology. Nonsurgical periodontal treatment was performed and serum levels of CRP were evaluated at baseline and 8 weeks after periodontal treatment. Results: Periodontal treatment resulted in significant reductions in CRP levels (p < 0.001). The difference between pre-and posttreatment CRP concentrations did not show any significant relationship with the severity of periodontitis. Conclusions: Periodontitis is an important source of systemic inflammation in CKD patients. Nonsurgical periodontal treatment can effectively reduce the serum level of CRP in these patients.

No abstract

Introduction: Dental caries and periodontal disease are among the most common infectious diseases in the world. DMFT (Decayed, Missing, Filled, Teeth), CPITN (Community Periodontal Index of Treatment Needs), and plaque indices are applied as suitable criteria for evaluating these two diseases and oral health. Given the significance of dental caries and periodontal disease, the objective of this study was to determine the incidence of dental caries and periodontal disease in the Iranian city of Shiraz. Material and Methods: The samples were evaluated in the four categories of medical, manufacturing, educational, and office centers within Shiraz, and then the DMFT, CPITN, and plaque indices in addition to nutrition status were all measured among them. Results: Having considered the DMFT to be below 15% and the CPITN less than 1.5 (the variables’ mean in the population under study), respectively, as resistant to dental caries and periodontal disease while at the same time taking into account the plaque index of less than 1.25 (mean) as the low level of this very index not disregarding the nutritional status of the population under study: the resistant individuals ratio to the two diseases equaling 10%, those individuals prone to these two diseases equaling 55%, the ratio of resistant people to periodontal disease and, simultaneously, prone to dental caries equaling 14%; and, lastly, the ratio of individuals resistant against dental caries simultaneously prone to periodontal disease equaling 20% (estimated). Conclusion: The research was performed in medical, manufacturing, educational, and office centers in Shiraz, Iran. There was no significant difference in terms of periodontal disease and dental caries between the four groups. [GMJ. 2012;1(2):66-71]