The effect of intravenous infusion of atropine on the pancreatic exocrine secretion in sheep was examined. Atropine was infused for 60min at the dose of 0 .01, 74.3%. Atropine also decreased protein concentration and amylase activity in pancreatic juice of which the reduction rates were 51.3% and 45.1%, respectively. These results indicate that the considerable part of basal juice flow and enzyme secretion are mediated by the cholinergic mechanisms.
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