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Flight simulators are examples of virtual environment (VE) systems that often give rise to a form of discomfort resembling classical motion sickness. The major difference between simulator sickness and other forms of motion sickness is that the former exhibits more oculomotor-related symptoms and far less actual vomiting. VEs of the future are likely to include more compellingly realistic visual display systems, and these systems can also be expected to produce adverse symptoms. The implications of simulator sickness for future uses of VEs include adverse consequences for users' safety and health, user acceptance, training effectiveness, and overall system performance. Based on data from a factor analysis of over 1000 Navy and Marine Corps pilot simulation exposures, a new scoring procedure for simulator sickness has recently been developed (Lane & Kennedy, 1988; Kennedy, Lane, Berbaum, & Lilienthal, 1992). The factor analytic scoring key provides subscales for oculomotor stress (eyestrain), nausea, and disorientation. Simulators are being examined in terms of these factor profiles to identify causes of simulator sickness. This approach could also be used in evaluating motion sickness-like symptomatology that occurs in connection with the use of VEs. This paper describes the use of the multifactor scoring of the Simulator Sickness Questionnaire (SSQ) in diagnosing sources of simulator sickness in individual simulators. Reanalysis by this new methodology was employed to standardize existing simulator sickness survey data and to determine whether relationships existed that were missed by the more traditional scoring approaches.

Assessment of cognitive and motor performance of bone marrow transplant patients prior to, during, and following intensive toxic chemoradiotherapy may provide an important adjunct to measures of physiological and medical status. The present study is an attempt to assess whether, as side-effects, these aggressive treatments result in cognitive performance deficits, and if so, whether such changes recover posttreatment. Measurement of cognitive ability in this situation presents special problems not encountered with one-time tests intended for healthy adults. Such tests must be sensitive to changes within a single individual, which emphasizes the crucial importance of high reliability, stability across repeated-measures, and resistance to confounding factors such as motivation and fatigue. The present research makes use of a microbased portable test battery developed to have reliable and sensitive tests which were adapted to study the special requirements of transplant patients who may suffer cognitive deficits as a result of treatment. The results showed slight but significant changes in neuropsychological capacity when compared to baseline levels and controls, particularly near the beginning of treatment. The sensitivity of the battery in detecting such subtle temporary changes is discussed in terms of past research showing effects of other stressors, such as stimulated high altitude and ingestion of alcohol, on these measures.