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OBJECTIVETo find whether placental laterality as determined by ultrasound can be used as predictor for the development of preeclampsia. METHODSThis prospective study was conducted on pregnant women attending the antenatal clinic of Regional Institute of Medical Sciences, Imphal, Manipur, from October 2012 till September 2014; 475 pregnant women attending antenatal clinic both OPD and IPD at 18-24 weeks of gestation without any high risk factor were subjected to ultrasound examination and placental location was determined. These cases were followed for the development of signs and symptoms of preeclampsia. RESULTOut of the total 475 women, 263(55.4%) had laterally located placenta and of them 45(17.1%) developed preeclampsia, while the remaining 212(44.6%) had centrally located placenta and of them 13(6.1%) developed preeclampsia. So, the overall risk of developing preeclampsia with laterally located placenta was 3.16 (odds ratio) and 95% confidence interval (1.65-6.03). The difference was found to be statistically significant, p value (0.0005) by χ 2 test. CONCLUSIONFrom the above study, we concluded that females with laterally located placenta determined by USG at 18-24 weeks of gestation have greater risk of developing preeclampsia. KEYWORDSPlacental laterality, Preeclampsia, Central placenta. HOW TO CITE THIS ARTICLE:Aggarwal P, Kangjam P, Terhase N. "Study on relation between placental laterality in second trimester ultrasound and development of preeclampsia at term

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