Introduction Diabetes mellitus (DM) is a metabolic disease that can cause many complications. The occurrence of urinary tract infection is also considered to be the cause of complications in patients with DM. This study aimed to evaluate the prevalence of urinary tract infection (UTI) and antibiotic-resistant bacteria found in urine culture from patients with DM in Surabaya, Indonesia. Methods This study was conducted with a retrospective cross-sectional study design, using a database of 1551 patients with DM admitted to Haji Hospital, Surabaya, Indonesia, from January 2017 to December 2018. Data regarding the bacteria isolated from urine and antimicrobial sensitivity were analyzed. Results The prevalence of UTI was 3.93% -61 patients were confirmed with urine culture for UTI diagnosis. The predominant isolates found were Escherichia coli (24.5%) and Enterococcus faecalis (8%). This study also showed multidrug-resistant organisms (MDRO) found in UTI such as Escherichia coli MDRO (3.3 %), Klebsiella pneumoniae MDRO (3.3%), Acinetobacter baumannii MDRO (1.6%), extended-spectrum beta-lactamase (ESBL) Escherichia coli (3.3%). The E. coli were sensitive to fosfomycin (93%), meropenem (93%) and nitrofurantoin (67%). No significant difference in the prevalence of UTI was found among ages, sex, and duration of disease in all patients with DM. Conclusions The cases of UTI seen in patients with DM show the importance of monitoring UTI occurrence in this patient category to ensure better treatment for these patients.

Nosocomial infections is still global public health problems. Along with the problems there are resistance bacterial problem to multiple classes of antibiotics, defined as multidrug resistance organisms (MDROs). Incidence rates of MDROs in ICU is higher than in other treatment unit. Rational antibiotic use and controlling the transmission of bacterial is important to avoid MDROs. The purpose of this study was to analyze Risk Differences of MDROs according to risk factors and hand hygiene compliance in ICU patients. This study used case control design with sample size was 20 patients for each case and control groups. Samples in cases group were patients infected by MDROs in ICU, while the samples in control group were patients in ICU didn’t infected by MDROs. The independent variable are long term use of antibiotic, length of stay, the use of ventilator, and hand hygiene compliance by health worker. Analyze data used OR (Odds Ratio) and RD (Risk Difference). The conclusion was that Risk Difference of MDROs infection by long term use of antibiotics (OR 10.23 95% CI 1.12 < OR < 93.35; RD = 0.47), length of stay (OR 7.36 95% CI 1.34<OR<40.55; RD = 0.44), the use of ventilator devices (OR 9.00 95% CI 1.64 < OR < 49.45; RD = 0.48) and hand hygiene compliance (OR 6.00 95% CI 1.46 < OR < 24.69; RD = 0.42). The conclusion was that maintaining hygiene before medical treatment, environment and health workers body should be implemented so can’t became a media for bacterial MDROs growth.Keywords: antibiotic,ventilator, length of stay, hand hygiene, MDROs

Nosocomial infections is still global public health problems. Along with the problems there are resistance bacterial problem to multiple classes of antibiotics, defined as multidrug resistance organisms (MDROs). Incidence rates of MDROs in ICU is higher than in other treatment unit. Rational antibiotic use and controlling the transmission of bacterial is important to avoid MDROs. The purpose of this study was to analyze Risk Differences of MDROs according to risk factors and hand hygiene compliance in ICU patients. This study used case control design with sample size was 20 patients for each case and control groups. Samples in cases group were patients infected by MDROs in ICU, while the samples in control group were patients in ICU didn’t infected by MDROs. The independent variable are long term use of antibiotic, length of stay, the use of ventilator, and hand hygiene compliance by health worker. Analyze data used OR (Odds Ratio) and RD (Risk Difference). The conclusion was that Risk Difference of MDROs infection by long term use of antibiotics (OR 10.23 95% CI 1.12 < OR < 93.35; RD = 0.47), length of stay (OR 7.36 95% CI 1.34<OR<40.55; RD = 0.44), the use of ventilator devices (OR 9.00 95% CI 1.64 < OR < 49.45; RD = 0.48) and hand hygiene compliance (OR 6.00 95% CI 1.46 < OR < 24.69; RD = 0.42). The conclusion was that maintaining hygiene before medical treatment, environment and health workers body should be implemented so can’t became a media for bacterial MDROs growth.Keywords: antibiotic,ventilator, length of stay, hand hygiene, MDROs