Objective: Alternative medicine has an important place in the fight against many diseases in human history. The biological activity of Glycyrrhiza glabra L. was investigated in this study.Material and Method: The root parts of the plant were extracted with ethanol. Antioxidant and oxidant potentials were determined using Rel Assay kits. Antimicrobial activity was tested against standard bacteria and fungus strains using the agar dilution method. Antiproliferative activity was determined by MTT test against Lung Carcinoma Cell Line (A549).Result and Discussion: As a result of the studies, the TAS value of the plant was measured as 8.770±0.171, TOS value as 14.590±0.191 and OSI value as 0.167±0.005. Inhibition of the plant extract was observed against standard bacteria and fungus strains at ranging from 50-200 µg/mL concentrations. In addition, it was determined that the plant extract displayed strong antiproliferative activity due to the increase in concentration. As a result of these studies, it has been determined that G. glabra can be used as an important natural antioxidant, antimicrobial and anticancer agent.
Medicinal plants are important natural materials used in the treatment of many diseases. In this study, total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of endemic Salvia absconditiflora Greuter & Burdet were determined. Plant samples were collected from Nigde and Erzincan (Turkey) provinces. Ethanol (EtOH) extracts of plant samples were extracted. TAS, TOS and OSI values were determined using Rel Assay Diagnostics kits. As a result of the studies, it has been determined that the samples of the plant collected from Nigde have higher TAS, TOS and OSI values. As a result, it has been determined that S. absconditiflora can be used as a potential antioxidant source due to high TAS values.
Objective: Plants are known to have many biological activities. In this study, the antioxidant, oxidant, antimicrobial and antiproliferative activities of Galium aparine L. were investigated.Material and Method: The antioxidant and oxidant potentials of the plant, the aerial parts of which were extracted with ethanol in a Soxhlet device, were measured using Rel assay kits. Antimicrobial activity against bacteria and fungi was determined using the agar dilution method. Lung carcinoma cell line (A549) was used to determine the antiproliferative activity.Result and Discussion: As a result of the studies, total antioxidant status (TAS) value of plant extracts was determined as 5.147 ± 0.237, total oxidant status (TOS) value as 18.679 ± 0.245 and oxidative stress index (OSI) value as 0.346 ± 0.018. Plant extracts were found to be effective against test microorganisms at concentrations of 50-200 µg/mL. In addition, it was determined that the antiproliferative activity of the plant extract showed potent effects depending on the increase in the extract concentration. Finally, it was determined that Galium aparine has high biological activity and can be used as a natural pharmacological agent in this context.
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