Background:The neonatal danger signs are a group of symptom presented in sick neonates that can. The Infant Mortality Rate (IMR) is calculated from the number of infant deaths 0<12 months per 1000 live births in an area in one year. The IMR in Banjarnegara Regency in 2018 was 14.1/1000 live births. Hence, the parents should know these signs to anticipate them early.These dangers signs are including: the inability of the baby to feed or vomiting, convulsion, weakness, shortness of breath, navel, fever, low body temperature, purulent eyes, diarrhea, jaundice. To increase the pregnant women's knowledge about the neonatal danger signs, we conducted education trought Video Media. The purpose of this study was to determine the effectiveness of video education on the knowledge of pregnant women about the neonatal danger signs at the Mandiraja 2 Health Center. Methods: This is an quasy experimental study with one group pre-test and post-test design. The sampling technique used was the total sampling method. Univariate analysis was used to find the frequency distribution in each variable. The bivariate test was conducted using the spearman rank test. Results:The results of this study showed the influence of audio visual media on the level of knowledge in pregnant women about the neonatal danger signs with a value of P-value of 0.000 (<0.05). Conclusion:The results showed that education using video was an effective approach to increase the knowledge of pregnant women about neonatal danger signs Keyword : neonatal danger signs, pregnant women knowledge, video education