Trichophyton rubrum is the most common causative agent of anthropophilic dermatophytosis worldwide. Treatment of dermatophytosis can use natural ingredients. In Indonesia, several medicinal plants have been used, one of which is red galangal (Alpinia purpurata (Vieill.) K. Sch). This study aims to determine the effectiveness of red galangal rhizome chloroform extract on the growth of Trichophyton rubrum. This study is a True Experiment study with Posttest Only With Control Group Design consisting of 8 treatments namely positive control, extract control, 0 mg/mL (negative control), 20 mg/mL, 30 mg/mL, 40 mg/mL, 50 mg/ml, and 60 mg/mL extract of red galangal rhizome chloroform with 3 repetitions. The antifungal activity test was carried out using the determination of Minimum Inhibitory Concentration (MIC), Minimum Fungicidal Concentration (MFC), and Bioautography Test. The results showed that the red galangal rhizome chloroform extract in the Agar Overlay Bioautography Test contained an inhibition zone on the growth of Trichophyton rubrum. The determination of MIC and MFC were 20 mg/mL and 40 mg/mL, respectively. The study concludes that the red galangal rhizome chloroform extract affects the growth of the fungus Trichophyton rubrum. Research can be continued by knowing more specifics about the bioactive compounds from the red galangal rhizome, which have antifungal activity against Trichophyton rubrum.

BackgroundGastrointestinal stromal tumors are the most common mesenchymal tumors in the gastrointestinal tract. Based on tumor size andmitotic index, WHO classified GIST into three prognostic groups which were benign, uncertain malignant potential, and malignant.Some studies revealed that there was variation in association between age, gender, tumor location, histopathologic type and prognosisof GIST patients. This study aimed to identify and analyze the association between clinicopathologic characteristics and WHOprognostic group in GIST patients at RSUP Dr. Mohammad Hoesin Palembang.MethodsThis study used 30 medical records of GIST patients during 01 January 2014 to 27 December 2018 in the Department of AnatomicPathology RSUP Dr. Mohammad Hoesin. Clinicopathologic characteristics and WHO prognostic group data were collected. Theassociation between clinicopathologic characteristics (age, gender, tumor location, histopathologic type) and WHO prognostic groupwere analyzed by chi-square test.ResultsFrom 30 subjects, 40% of the patients aged 52-58 years.There was no gender predilection. A total of 33.3% of the GISTs were locatedin the small intestine. Majority of histopathologic type was spindle cell type (93.3%). Bivariate analysis showed there were no significantassociation between clinicopathologic characteristics: age (p=0.811), gender (p=0.682), tumor location (p=1.000), histopathologic type(p=0.469) and WHO prognostic group.ConclusionThere was no significant association between clinicopathologic characteristics and WHO prognostic group in GIST patients at RSUPDr. Mohammad Hoesin Palembang. We suggest doing a cohort study about association between clinicopathologic characteristics andsurvival rate in GIST patients.

Quality of life is a person's ability to enjoy normal life activities. Healthy living is part of the quality of life, because it is healthy not only physically but also mentally and socially healthy. Oral health is an inseparable part of general health because dental and oral health conditions can affect daily life. This study aims to determine the relationship between dental caries and quality of life in early childhood. This cross sectional study conducted in February 2021 at PAUD Baiturrohim, Palembang. The subject consisted of 67 children taken by simple random sampling. Dental caries status was measured using the def-t index and children's quality of life was measured using the Early Childhood Oral Health Impact Scale (ECOHIS). Data were analyzed using the Chi-Square test with a 95% confidence interval. The def-t index category in early childhood in Baiturrohim PAUD with very high criteria was 56.7%, high criteria  was 16.4%, moderate and low criateria were 10.4% respectively and very low criteria was 6%. The quality of life in early childhood in Baiturrohim PAUD with bad criteria was 53.7%, moderate criteria was 25.4%, and good criteria was 25.4%. It was found that there is a significant relationship between the incidence of dental caries and quality of life (p0.05).

Background : Typhoid is one of the infection diseases that causes the increasing of nutrition need. However, in fact, there are still many patients who get soft diet/ porridge that will reduce feed intake.Objective : This study aims to determine the effect of rice on diet (energy, protein, fat and carbohidrat) intake and care typhoid patients.Method : This research study is an experimental Pre Static Group Comparison. Sampling was non-randomized purposive sampling.The number of sample was 34 typhoid patients. The treatment group was given rice diet and control group was given soft diet/ porridge, intake (energy, protein, fat and carbohidrat) observed comstok method. The duration of treatment was collected from data. Statistic test that was used was independent - t test if the data are normally distributed and Maan - Whitney test if the data are not normally distriuted.Results : Giving rice diet will increase energy, protein, fat, carbohydrates typhoid patients was10.20%, 7.53%, 8.66%, and 8.19%. There is an influence in giving rice diet toward energy, protein, fat and carbohydrates absorbtion of Thypoid patients(p: 0.000, p: 0.006, p: 0.008, p: 0.011) and there is no influence in giving rice diet and porridge diet toward the duration of treatment (p: 0305).Conclusion: Giving rice diet will increase energy, protein, fat and carbohydrates absorption of typhoid patients but doesnot influence the duration of treatment.