Introduction: Psoriasis is an inflammatory skin disease that is characterized by T-cell-mediated hyperproliferation of the keratinocytes. It develops through immune-mediated mechanisms and is defined as an immune-mediated inflammatory disease. The inner ear is susceptible to inflammatory attacks, and vertigo and dizziness can occur as a complication. There is little information about psoriasis and the vestibular system. Objective: This study aimed to investigate the cervical vestibular-evoked myogenic potential (cVEMP) results of psoriasis patients and the effect of psoriasis on the vestibular system. Materials and Methods: Randomly selected and included in the study were patients who had been admitted to the Dermatology Outpatient Clinic of the Afyon Kocatepe University Medical Faculty, between November 15, 2017, and March 15, 2018, with the diagnosis of psoriasis, in addition to a healthy control group. This research was designed as cross-sectional study. Ethics committee permission was received. Both cVEMP and distortion product otoacoustic emission (DPOAE) tests were administered to all of the participants. Values were compared between the control group and psoriasis patients. Results: The study included 43 psoriasis patients and 40 controls. The duration of treatment of the patients and the drugs that they were using were noted. The psoriasis patients had lower p13–n23 amplitude differences in their cVEMP tests ( P < .05). These patients also had lower signal to noise ratio values, at 4 and 6 kHz, on their DPOAE tests ( P < .05). Conclusion: Psoriasis is an immune-mediated inflammatory disease that can be associated with vestibulocochlear dysfunction.
endon kılıfının dev hücreli tümörü (TKDHT); eklem, bursa veya tendon kılıfı sinoviyumunun benign, lokal agresif, proliferatif bir hastalığıdır. 1 En sık olarak el palmar yüzde nodüler kitle ile kendini göstermektedir. Dermoskopisi ile ilgili literatür bilgisi oldukça azdır.Bu çalışmada, TKDHT'nin dermoskopik ve histopatolojik özelliklerine ve ayırıcı tanısına dikkat çekilmesi amaçlanmıştır. OLGU SUNUMUOtuz üç yaşındaki erkek olgu, son dört aydır parmakta oluşan şişlik şikâyeti ile başvurdu. Hastadan bilgilendirilmiş onam formu alındı. Öyküsünden lezyonun ağrısız olduğu ve geçirdiği trafik kazası sonrası ortaya çıktığı öğrenildi. Dermatolojik muayenesinde sol el üçüncü parmak palmar yüzde 0,7x0,6 cm çaplı, sarımsı beyaz renkte, üzerinde yer yer telenjiektazilerin izlendiği, mobil olmayan sert nodüler lezyon görüldü (Resim 1). Nodülün dermoskopik incelemesinde, beyaz skar benzeri yapısız zeminde yer yer Turkiye Klinikleri J Dermatol. 2019;29(2):89-91 89 Re ce i ved:
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