Dengue hemorrhagic fever (DHF) in the community can have an impact of panic, death, and reduced age of hope in the family. Research on the quality of life of DHF pediatric patient who got the treatment of crystalloid and colloid fluids has never been done before. The purpose of this study was to determine the quality of life of DHF pediatric patients who received crystalloids and colloids with PedsQL instruments. The study design was a cohort with block randomization. The inclusion criteria in this study were hospitalized DHF pediatric patients aged one month -18 years from February to May 2018. The exclusion criteria were DHF patients who came with referrals from other hospitals who had received fluid therapy. Research data include the length of stay (LOS) and quality of life score with the PedsQL questionnaire. The statistical analysis was using an independent ttest and the Mann Whitney test. The length of stay for the crystalloid group is five days longer than the colloid group, which is four days. From a total of 48 subjects studied, the score for the physical function of the crystalloid fluid group 84.54 ± 9.90 was higher than the colloid group of 77.58 ± 19.30 (p = 0.125). The emotional functions in the crystalloid group obtained a score of 81.88 ± 12.14 higher than the colloid group, i.e., 79.17 ± 18.5 (p = 0.552). The social function in the crystalloid group had a score of 92.08 ± 8.84 higher than the colloid group of 86.67 ± 13.96 (p = 0.232). The school functions in the crystalloid group had a score of 50.42 ± 33.68 higher than in the colloid group of 37. 92 ± 36.62 (p = 0.225). The results of this study showed that the crystalloid group had a higher quality of life score compared to the colloid group, although it was not significant.

AbstrakTerapi steroid pada anak dengan pneumonia merupakan terapi tambahan yang memiliki aktivitas sebagai penghambat inflamasi yang menekan ekspresi sitokin proinflamasi dan berpotensi mencegah respon inflamasi. Beberapa penelitian menunjukkan pemberian steroid tidak memberikan pengaruh dalam pengobatan pada pasien pneumonia, tetapi pada penelitian lain menunjukkan pemberian steroid mengurangi rata-rata lamanya pasien dirawat di rumah sakit. Tujuan dari penelitian ini adalah untuk melihat pengaruh pemberian steroid terhadap rata-rata lamanya pasien dirawat di rumah sakit (LoS) dan tanda klinis pasien anak dengan pneumonia. Penelitian yang dilakukan merupakan penelitian observasional dengan metode prospektif yang dilakukan di Rumah Sakit PKU Muhammadiyah Bantul Yogyakarta pada bulan September 2015 hingga Januari 2016. Lima puluh satu pasien digunakan sebagai subjek penelitian. Penelitian ini terdiri dari 2 kelompok yakni kelompok non-steroid terdiri dari 25 pasien dan kelompok steroid terdiri dari 26 pasien. Kelompok non-steroid dan steroid masing-masing memiliki nilai rata-rata lamanya pasien dirawat di rumah sakit 5 (3-10) hari dan 4 (3-10) hari. Durasi tanda klinis pasien kelompok steroid dan kelompok non-steroid berturut-turut adalah 2 (0-6) hari dan 2 (0-7) hari untuk demam, batuk 4 (1-10) hari dan 5 (2-10) hari, sesak 1 (0-5) hari dan 1 (0-10) hari, retraksi 1 (0-5) hari dan 1 (0-9) hari. Kesimpulan dari penelitian ini adalah steroid sebagai terapi tambahan memberikan efek yang tidak berbeda bermakna terhadap nilai length of stay dan tanda klinis pasien anak dengan pneumonia.Kata kunci: Anak, length of stay, pneumonia, steroid Steroids Effect as Adjuvant Therapy toward Length of Stay and Clinical Symptoms in Pediatric with Pneumonia AbstractSteroid therapy in children with pneumonia is an adjuvant therapy that has inhibitor inflammatory activity which can suppress the expression of proinflammatory cytokines and potentially prevent the inflammatory response. Some studies showed that steroids did not give beneficial effects in the treatment of patients with pneumonia, while the other studies showed that steroids can reduce the length of stay in hospital. The purpose of this study was to observe the effect of steroid on the length of stay and clinical symptoms in pediatric patients with pneumonia. This was an observational study with a prospective method in patients with pneumonia in PKU Muhammadiyah Bantul Hospital Yogyakarta from September 2015 until January 2016. A total of fifty one patients participated as subjects of this study. This study consisted of two groups, which were non-steroid group (n=25) and steroid group (n=26). Group of non-steroid and steroid had average value of length of stay of 5 (3-10) days and 4 (3-10) days, respectively. The duration of clinical symptoms of patients in the steroid and non-steroid group in a row was 2 (0-6) days and 2 (0-7) days for symptoms of fever, 4 (1-10) days and 5 (2-10) days for symptoms of cough, 1 (0-5) days and 1 (0-10) days for symptoms of shortness, and ...

AbstrakDemam berdarah dengue (DBD) merupakan penyakit infeksi yang disebabkan oleh virus dengue. Kasus DBD di Kabupaten Bantul pada tahun 2016 berjumlah 1.706 dengan 13 kematian. Salah satu kunci keberhasilan terapi pada pasien DBD adalah menjaga tercukupinya kebutuhan cairan pasien selama fase kritis. Penelitian ini bertujuan untuk mengetahui perbedaan pemberian terapi cairan inisial terhadap perbaikan klinis, laboratoris dan lama rawat inap dibandingkan terapi standar WHO pada pasien dengue fever (DF) dan dengue hemorrhagic fever (DHF) di bangsal anak RS PKU Muhammadiyah Bantul. Penelitian ini dilakukan di bangsal anak RS PKU Muhammadiyah Bantul pada bulan Februari sampai dengan Juni tahun 2018 menggunakan metode eksperimental single blind randomised clinical trial pada dua kelompok yaitu cairan standar WHO (n=24) dan cairan inisial (n=24). Hasil yang diukur yaitu luaran terapi suhu badan, hematokrit, trombosit dan lama rawat inap. Perbedaan antarkelompok dianalisis dengan unpaired t-test dan Mann-Whitney. Berdasarkan hasil penelitian, kedua kelompok tidak menunjukkan perbedaan bermakna terhadap rata-rata suhu badan dan hematokrit (p>0,05), sedangkan kedua kelompok menunjukkan perbedaan yang bermakna terhadap rata-rata peningkatan trombosit dan lama rawat inap (p<0,05). Hal ini menunjukkan bahwa kelompok cairan inisial memiliki rata-rata lama rawat inap lebih cepat 4,00±0,7 hari dibanding kelompok standar WHO yang disertai dengan peningkatan trombosit selama menjalani rawat inap. Simpulan dari penelitian ini adalah pemberian terapi cairan inisial tidak memberikan perbedaan yang signifikan terhadap rata-rata suhu badan dan hematokrit, sedangkan efektivitas antara kedua kelompok menunjukkan perbedaan yang bermakna terhadap rata-rata peningkatan trombosit dan lama rawat inap.Kata kunci: Cairan inisial, demam berdarah dengue, hematokrit, lama rawat inap, suhu badan, trombosit AbstractDengue hemorrhagic fever (DHF) is an infectious disease caused by the dengue virus. The number of dengue cases in Bantul Regency in 2016 was 1,706 with 13 deaths. One of the keys to successful therapy in DHF patients is to maintain adequate fluid requirements for patients during the critical phase. This study aimed to determine differences in initial fluid therapy for clinical, laboratory improvement and length of stay compared to WHO standard therapy in dengue fever (DF) and DHF patients in pediatric ward PKU Muhammadiyah Bantul Hospital, Yogyakarta, Indonesia. This research was conducted in the pediatric ward of PKU Muhammadiyah Bantul Hospital in February 2018 to June 2018 using a single blind randomized clinical trial experimental method. Samples were divided into two groups, namely WHO standard fluid (n=24) and initial fluid (n=24). The results measured were body temperature, hematocrit, platelets and length of stay. Differences between groups were analyzed using unpaired t-test and Mann-Whitney. The two groups showed a significant difference toward the increase in platelets and length of stay (p<0.05). This suggests that the init...

Diarrhea is the second leading cause of death in children under 5 years after pneumonia with a mortality prevalence of 8%. Diarrhea is a digestive disease with signs of bowel movements with a sudden consistency of loose stools 3 times or more in 24 hours, mostly caused by microorganisms (bacteria and viruses). The cure rate for diarrhea after receiving fluid replacement therapy and antibiotics for diarrhea caused by bacteria is quite high, but the mortality rate due to diarrhea is still high, therefore there needs to be an effort to add therapy to improve patient clinical outcomes. Vitamin D is known to play a role in the body's defense function, both in natural and adaptive immunity and plays a role in the body's defense in cases of infections, allergies, and autoimmunity. This study is an experimental double blind randomized clinical trial which was analyzed using Kaplan Meier. The research subjects were children aged 6 months to 18 years who were divided into two groups, namely the treatment group (n = 35) and the control group (n = 35). The treatment group received vitamin D and for the control group received a placebo. The data taken includes the results of the frequency of defecation of patients. The results of this study indicate that vitamin D is effective in accelerating the reduction in the frequency of defecation in children with diarrhea.  Keywords: Diarrhea, Vitamin D, Defecation, Kaplan Meier

Pendahuluan: Kunci keberhasilan terapi pada demam berdarah yaitu tercukupinya kebutuhan cairan. Hal penting yang perlu diperhatikan dalam terapi cairan yaitu jenis cairan dan jumlah cairan yang diberikan. Tujuan: Tujuan dari penelitian ini untuk mengetahui efektivitas perbedaan jenis cairan terhadap perbaikan klinis, laboratoris dan lama rawat inap pasien demam berdarah anak di Rumah Sakit PKU Muhammadiyah Bantul. Metode: Pasien anak demam berdarah yang memenuhi kriteria inklusi diberikan cairan kristaloid (ringer laktat) atau koloid (gelatin) dan dilakukan pemantauan suhu tubuh, hematokrit, trombosit dan lama rawat inap. Hasil dianalisis mengunakan SPSS dengan unpaired t test. Hasil: Kedua kelompok menunjukkan perbedaan yang bermakna (p < 0,05) terhadap nilai trombosit (24 dan 48 jam pemberian cairan), nilai hematokrit (72 jam pemberian cairan) dan lama rawat inap sedangkan kedua kelompok tidak menunjukkan perbedaan bermakna (p > 0,05) pada gejala demam (suhu tubuh). Kesimpulan: Terapi cairan koloid memberikan pengaruh yang lebih baik terhadap perbaikan gejala klinis dan laboratoris serta mengurangi lama rawat inap pasien.