Objectives: The current prevalence of Total Hip Replacement (THR) in adult patients in Slovakia ranges in about 5 200 cases per year with expenditures about 10.545.600 € . The THR has a great impact on the quality of life (QoL) and the physical ability too. Till now in the Slovak Republic was not realised the study like this one. MethOds: 118 patients, 59 men and 59 women, with THR were studied. The average age was 62,24 y., the average duration of illness was 7,75 y. and the average waiting time to surgery was 0,73 y. QoL and the taking care about himself (TCaH) was evaluated after THR on the numeric scale from 0 to 10 (0 for the worst, 10 for the best) and pain (0 for the best, 10 for the worst) by patients themselves Results: QoL has increased from 4,24 to 6,30 after THR. The ability to take care about himself has decreased from 6,38 to 3,45 after THR. Pain has decreased from 7,85 to 3,32 after THR, and after spa stay from 3,04 to 2,03. The loss of money in productive age patients was 216,63 € . The score of physical health by SF 36 questionnaire was 50,94 points and score of mental health was 65,41 points, the average score was 57,98 points. 35 patients from 45 patients were able to come back to work after THR. cOnclusiOns: THR has a great impact on QoL, pain and on the TCaH too. There was not statistical difference between men and women in all evaluated parameters. The early/earlier made THR could have an important influence on better QoL and pain development.There is a good correlation between results from numeric scale and SF 36.