Background: Data from International Labor Organization (ILO) at 2005 shows that there are 250 million case of diseases that related to occupation which can also cause 300.000 death in the world with annual incidence rate of work related lung disease around 1:1000 worker. Laundry worker was included as group that has risk of having occupational pneumoconiosis. Method: This is a descriptive study using total sampling with sample number 24 patient, this study was done in Laundry Installation of Rumah Sakit Umum Pusat Haji Adam Malik Medan on November 2016. Examination was done by using questionnaire, physical examination, daily PEF (before and after working) for 14 days, spirometry, total room dust, total room bacterial colonization. Factors (age, sex, working duration, smoking history, p.2,5 dust exposure, bacterial exposure, safety equipment usage, and nutritional status) that had potential of affecting the decreasing lung function was assessed. Result: From PEF examination, we found mean variability 3.1%. from all worker, there are 9 workers that had decreasing lung function ≥3, 1%. From examination result of 9 sample, decreasing lung function mostly caused by smoking (55%) and p.2,5 dust exposure (66%) Conclusion: Smoking and p.2,5 dust exposure is the most common factors that affected decreasing lung function in laundry worker. (J Respir Indo 2018; 38(2): 109-14)

Background: Military soldiers are army personnel who are required to have good physical endurance and optimal fitness, include. So, it's needed physical exercise, include to be able to improve lung function. One parameter that can reflect physical fitness are lung function and m VO2max. This study aims to determine whether there is a relationship between physical exercise in the form of 2-mile jogging with increased lung function and VO2max of military soldiers Kodam 1 Bukit Barisan Methods: This research is an experimental study carried out in February-April 2019 against the TNI soldiers of the Bukit Barisan Military District 1. The research subjects were divided into two groups, group 1 who underwent regular 2-mile jogging exercises 3-5 times a week with a duration of 25 minutes for 2 months, and group 2 who underwent non-routine jogging exercises (less than 3 times a week). Lung function was assessed by spirometry. Results: As many as 68 military soldiers were involved in this study which were divided into two groups, 38 people in the group 1 who routinely trained and 30 people in group 2 that did not routinely practice. Group 1 VEP1 values were higher than group 2 (p=0.03). No significant differences in terms of KVP, MVV and VO2max in both groups. Lung function of smokers were lower than non-smokers, but not statistically significant. Conclusion: There were significant differences in VEP1 values between military soldiers who routinely and did not routinely undergo 2-mile jogging exercises.

Latar belakang: Pekerja industri keramik sering terpajan bahan silika keramik. Tujuan penelitian ini adalah untuk mengetahui hubungan antara pajanan silika dengan hasil uji fungsi paru dan foto toraks pekerja.

Background: Untreated or undertreated, pulmonary tuberculosis could cause severe complications until death. After treatment, residual lesions might occur. The presence of residual lesions is varied, including: fibrosis, cavity, bronchiectasis and calcification. Transforming growth factor-β (TGF-β) is a cytokine associated with lung inflammation, which plays a role in lung fibrosis. However, only a few studies have assessed the serum level of TGF-β in post-treatment tuberculosis patients. The main objective of this study was to determine the relationship between TGF-β levels and pulmonary fibrosis in patients with pulmonary tuberculosis. Methods: Among 51 patients that had undergone anti-tuberculosis treatment were observed, consisting of 31 men, 20 women. Of all patients, there were 26 people with a smoking history, including 25 men and 1 woman. All patients had been recovered, confirmed by clinical state, laboratory and radiology examination. The ELISA test was performed to measure TGF-β level, while chest X-ray was used to evaluate for the occurence of pulmonary fibrosis. Results: The mean level of TGF-β in patients with lesion (+) was 7628.02 pg/mL (SD: ±4928.38) while the mean level of TGF-β in patients with lesion (-) was 2315.11 pg/mL (SD: ±505.83). Statistical test showed a significant relationship between TGF-β level and fibrosis lesion (P

BACKGROUND: Carbon monoxide (CO) is air pollutants that have continued to increase in level. It might affect the body through the binding of CO with hemoglobin (Hb) in blood to form carboxyhemoglobin (COHb). In addition to cigarettes, another pollutant that might affect the COHb levels in the blood is the smoke produced from grilled food. AIM: Thus, this research was done to identify the difference in COHb levels in blood between grilled and non-grilled food vendors. METHODS: A comparative analysis study with a cross-sectional design was done between October and November 2020 at Jalan Dr. Mansyur, Medan. The sample for the measurement of COHb levels of each subject was taken from blood plasma. COHb levels were measured with Human COHb Elisa Kit, Size 96 Wells, Brands Bioassay TL at the integrated research laboratory of Universitas Sumatera Utara. Data analysis was done using SPSS version 24.0. Normality test of COHb levels in blood between grilled and non-grilled food vendors was done using Shapiro–Wilk test, where p > 0.05 indicated a normal distribution of data. RESULTS: A total of 50 subjects (25 from grilled food vendors and 25 from non-grilled food vendors) met the research criteria. Thirty-two subjects (64%) aged 20–30 years, where 19 of them were grilled food vendors (59.4%) and 13 (40.6%) were non-grilled food vendors. COHb levels were 500.22 ng/ml with minimum and maximum levels of 106.21 ng/ml and 1204.14 ng/ml observed, respectively. The median of COHb levels in grilled food vendors (352.81 ng/ml) was found to be lower than that in non-grilled (513.58 ng/ml). Comparative analysis results showed p = 0.204 (p > 0.05). CONCLUSION: There was no significant differences in COHb levels in blood between grilled and non-grilled food vendors in Medan.