Antibiotic resistance possesses a serious challenge in the treatment of Urinary Tract Infections (UTIs). This study was therefore designed to determine the antibiogram of K. pneumoniae isolated from individuals presenting with UTIs in communities within Enugu state. A cross-sectional study was conducted from February, 2021 to June, 2021 and a total of 735 patients with community-acquired UTIs in Enugu state, Nigeria, were involved in the study. The patients were assessed clinically and microbiologically for Klebsiella pnuemoniae and antibiogram of the isolates were investigated. Out of 77 isolates of Klebsiella pneumaniae obtained, 29 (37.7%) showed multiple resistant to the antibiotics used, whereas 48 (62.3%) were either susceptible or intermediate. Of all the antibiotics tested, meropenem showed the highest recorded sensitivity to the test organism 63(19.93%), whereas the least sensitivity was observed in co-amoxiclav 11 (3.48%). Antibiogram of urinary K. pneumoniae isolated from rural dwellers showed a significantly high resistance to commonly used antibiotics; thus, the need for regular awareness campaign and antimicrobial resistance surveillance to increase knowledge, improve infection control measures, and check abuse of antibiotics.

Cervical-cancer is preventable through early detection of cervical intraepithelial neoplasia that heralds the disease via cervical-cancer screening, yet its mortality is still high especially in developing countries. In Nigeria, researchers have attributed the high cervical-cancer mortality to low uptake of cervical-cancer screening predicated on wrong perception and low knowledge of cervical-cancer and cervical-cancer screening; lack of cervical-cancer screening programme; inadequate community support for cervical-cancer screening and gap in screening skills among health-workers where opportunistic cervical-cancer screening exists. This study aims to identify context-specific interventions for improving cervical-cancer screening uptake and reducing cervical-cancer burden in Nigeria. Secondary data was used for the study.Literature were obtained from Global Health, Popline and PubMed databases; WHO and other relevant websites using Eldis search engine; and from libraries in the University of Leeds and WHO in Geneva. Interventions for improving cervical-cancer screening uptake were analyzed using a set of appraisal criteria which include; technical and cost effectiveness, organizational, gender, cultural and political feasibility to determine their applicability and transferability in Nigeria. Broad interventions identified are; intervention aimed at correcting perception, improving knowledge and increasing access to cervical-cancer screening. Reducing the burden and impact of cervical-cancer in Nigeria will depend on implementation of these interventions by stakeholders.

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