Background. The ongoing pandemic of a new coronavirus infection (COVID-19) determines the relevance of the analysis of epidemiological patterns of SARS-CoV-2 spread among the population of the Russian Federation.Aim — study of the manifestations of the epidemic process of COVID-19 in the Russian Federation in 2020–2022.Materials and methods. A retrospective epidemiological analysis of the incidence of COVID-19 in the Russian Federation was carried out from 03/30/2020 to 04/24/2022. The data from the Rospotrebnadzor report No. 970 “Information on cases of infectious diseases in persons with suspected new coronavirus infection”, information portal Stopcoronavirus.rf, etc. were used. The presence of SARS-CoV-2 RNA was confirmed by real-time RT-PCR.Results and discussion. The analysis of the manifestations of the epidemic process of COVID-19 in the Russian Federation in 2020–2022 showed the presence of two stages which differed depending on the influence of the biological factor and the ongoing anti-epidemic measures. There was a pronounced trend in the development of the epidemic process, starting from megacities (Moscow, Moscow region and St. Petersburg), which are major transport hubs and centers of migration activity of the population, to the regions of the Russian Federation. The SARS-CoV-2 pathogenicity has been shown to decrease with each subsequent cycle of the rise in the incidence of COVID-19 against the background of the increased contagiousness of the virus.Conclusion. As a result of the study, risk areas (megacities) and risk groups were identified.

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Background. The pandemic of the new coronavirus infection COVID-19 determines the relevance of conducting a study of the gender age structure of hospitalized and deceased among the population of Moscow on the example of one of the city clinical hospitals in 2020 and 2021. The aim of the work is to identify the patterns of the epidemic process of COVID-19 in connection with the gender and age characteristics of hospitalized adults and to establish the sex and age groups most susceptible to hospitalization and mortality from COVID-19. Materials and methods. The analysis of the structure of hospitalized and deceased from COVID-19 in the context of their gender and age composition was carried out. The data of the statistical accounting form F-60u/lech "Journal of infectious diseases" of adults hospitalized in one of the city clinical hospitals of Moscow in 2020 and 2021 were used. Data processing was carried out by a set of standard statistical methods. To identify the true risk groups for hospitalization and mortality, a statistical correction of the sex and age composition of the population of Moscow was used. Results and discussion. Using standard statistical methods in combination with the use of statistical correction of sex and age composition, data on the true risk groups for hospitalization and mortality among the population of Moscow in 2020 and 2021 were obtained. Conclusion. The results obtained in our independent study on the true risk groups for hospitalization and mortality among the population of Moscow complement and introduce new knowledge about the true risk groups for hospitalization and mortality in COVID-19. The patterns identified in this epidemiological analysis are an important component of epidemiological surveillance for making managerial decisions to prevent the spread of SARS-CoV-2 and planning for the provision of inpatient medical care to established gender and age risk groups.

The article attempts to articulate the conceptual characteristics of an up-to-date tertiary-level foreign language coursebook. In order to meet the requirements of modern national educational standards and be in line with the aims of foreign language teaching, a new generation coursebook, whether printed or electronic, is to be based on a set of such general didactic principles as competency-based approach, interdisciplinary approach, multilevel approach, modularity, and proximal development as well as such specific language teaching principles as authenticity, up-to-dateness, informativeness, and functionality. The authors substantiate the need for an integrative approach to developing an innovative coursebook, which consists in blending a printed and an electronic version, thus allowing for a more optimal organisation of the teaching-learning process due to a more rational proportion between classroom and self-study activities. The effective organisation of the process, in its turn, is instrumental in achieving the aims and goals of foreign language teaching. New generation coursebooks can be used not only to organise independent and self-study activities of full-time students of higher education, but also to provide a basis for various forms of distant learning, which will enable up-country students to receive high-quality (language) education.