Our research goal was to reveal priority food products (FP) distributed on a regional consumer market as per health risks they caused for population. The research was accomplished with statistic, analytical, and mathematical procedures as well as using comparative analysis procedure. We analyzed laboratory data on sanitary-chemical and physical-chemical parameters collected over 2010–2019; our analysis revealed there were insignificant risks excluding FP contamination with nitrates. Special attention should be paid to microbiological contamination as overall parameters related to it remain steady over the compared 5-year periods. We also have detected unfavorable trends as average parameters have grown authentically over the last 5 years against 2010–2014 when it comes to fruit and vegetables, poultry, fish products, and alcoholic beverages with growth rates varying from 3.53 times to 1.44 times. Having accomplished all the necessary calculations, we established that in Buryatia, just as in the Russian Federation in general, there were no food products that could cause extremely high health risks. But at the same time, the examined regional market had certain differences from the overall Russian one. High health risks were caused by poultry and it was not the case in the country in general. Bakery, confectionary, and fish products that caused high health risks in the country as a whole caused only significant risks in the region. Milk products also were assigned into a high risk category. We performed complex assessment and classified FP as per their quality and safety using health risk analysis methodology; it allowed us to determine priorities resulted from microbiological contamination of poultry and this fact is vital for population health in Buryatia.

In this study, we aimed to estimate the association between the rs9939609 FTO (fat mass and obesity associated) polymorphism and a risk of overweight in children living in the Baikal region. We performed a case – control study that included 113 schoolchildren living in industrial centers of the Baikal region (Irkutsk, Angarsk, and Ulan-Ude). Anthropometric parameters were measured and body mass index was calculated with its values being ranked in accordance with the WHO BMI curves depending on a sex and age. Genotyping of the rs9939609 FTO polymorphism was performed by allele-specific amplification with real-time results detection. To assess likelihood of an association between the FTO gene allele and overweight and obesity, relative risk (RR) and 95 % confidence interval (CI) were calculated. The assessment revealed the A allele of the rs9939609 FTO polymorphism to be by 1.29 times more frequent in the examined children with overweight and obesity (48.44 %) than in the children form the reference group (37.65 %). The FTO rs9939609 polymorphism was authentically associated with likelihood of elevated risks of overweight and obesity in children with the homozygous AA genotype (RR = 2.806, 95 % CI: 1.650–4.772; STD = 0.271). Our study confirms that the rs9939609 polymorphism of the FTO gene is a risk factor of overweight and obesity for children from the Baikal region who have the A allele of the homozygous AA genotype. Prevailing frequency of the TT genotype (29.2 %) as compared with the AA genotype (10.62) is likely due to influence of assimilation processes on urbanized territories in the Baikal region.