The article presents data on the invasiveness of pigs and sheep by associated parasitocenoses. Approximately one-third of newborn animals showed signs of acute parasitocenosis. About 80% of diseased lambs died. In the course of the research, intestinal sticks were isolated from strain K99 and K129, which are typical pathogens of colibacteriosis of piglets, eggs and larvae of the Strongiloid type (Haemonchus contortus). A treatment regimen was developed with the use of fenbendazole and multibacterin. In pigs, the high percentage of animals with an acute course is explained by the associated parasitocenosis, in which blastocyst invasion occurs against the background of colibacteriosis.