The corneal endothelium of 179 healthy persons (327 eyes), 4-89 years of age. as photographed through a non-contact specular microscope. From the histograms of the cell areas of each eye, other parameters were derived and subjected to computerized statistical analysis. In addition, photographs of both eyes of one person were taken on two different days and examined to determine the reproducibility of the method. The known age-dependent increase in the mean cell area as well as the decrease of the cell density with age could be confirmed. Other parameters that increase with age are the variability of the mean cell area and the maximum cell area; the latter correlates so well with age and is so easily measured that this parameter may facilitate further morphometric evaluations. For these age-dependent correlations not only regression lines but also third-rank regression curves, which seem to fit better, were calculated. Finally, age-independent parameters were found that may serve as potential additional criteria for a qualitative evaluation of the individual corneal endothelium.
A novel propulsion method suitable for micromachining is presented that takes advantage of Helmholtz resonance, acoustic streaming, and eventually flow entrainment and thrust augmentation. In this method, an intense acoustic field is created inside the cavity of a Helmholtz resonator. Flow velocities at the resonator throat are amplified by the resonator and create a jet stream due to acoustic streaming. These jets are used to form a propulsion system. In this paper a system hierarchy incorporating the new method is described and the relevant governing equations for the Helmholtz resonator operation and acoustic streaming are derived. These equations can predict various device parameters such as cavity pressure amplitude, exit jet velocity and generated thrust. In a sample embodiment, an electrostatic actuator is used for generation of the initial acoustic field. The relevant design parameters for the actuator are discussed and an equivalent circuit model is synthesized for the device operation. The circuit model can predict the lowest order system resonance frequencies and the small signal energy conversion efficiency. A representative resonator performance is simulated and it is shown that velocities above 16 m/s are expected at jet nozzles. The calculated delivered thrust by this resonator with 0.7 lm diaphragm displacement amplitude is 3.3 lN at the resonance frequency.
Abstract— Because the pixel area of liquid‐crystal‐on‐silicon (LCoS) microdisplays is about 100 times smaller than that of direct‐view liquid‐crystal displays (LCDs), the limitations of the conventional alignment by brushing are obvious: Scratches and particle contamination caused by brushing become visible due to the strong optical magnification required for LCoS LCDs both in front or rear projection. As an alternative, photoalignment with the linear photo‐polymerization (LPP) technology avoids the generation of defects, thus increasing production yields considerably. For application in LCoS LCDs, alignment layer materials must match the high‐voltage holding ratio (VHR) specifications of TFT‐LCDs. The VHR performance of the newly developed second‐generation LPP materials is shown to be similar to standard TFT polyimides used for conventional brushed alignment. We report investigations of pretilt‐angle generation by photoalignment on reflective CMOS substrates. UV light reflected from the CMOS surface during LPP exposure affects the resulting pretilt angle. Compared to pretilt angles on transmissive substrates, the reflected UV light can induce lower, higher, or identical pretilt angles, depending on LPP material properties. In any case, the pretilt angles are well defined, which results in perfect LCD alignment.
A propulsion system based on acoustic streaming generated by Helmholtz resonators is presented. High frequency (>60 kHz) electrostatically driven micromachined Helmholtz resonators constitute the basic unit of the system. Microjets produced at the exit of these resonators can be combined to form a distributed propulsion system. A high yield (>85%) fabrication process is introduced for fabrication of individual as well as arrays of resonators. The fabrication results for ten different designs are presented. About 1000 resonators of similar design cover the surface of a 4-in. wafer, effectively converting it to a distributed propulsion system. A number of characterization methods such as monitoring the harmonics of the drive current, laser interferometry, hot-wire anemometry, acoustic spectrum measurement and video particle imaging are used to determine the structural and fluidic behavior of different resonator designs. Collapse and recovery times of the diaphragm in the electrostatic actuator of the resonator are characterized and reduced to less than 10 ls by optimizing the perforation design. The occurrence of acoustic streaming in the micron-scale is verified via video particle imaging. The jet streams produced with pulse drive at low frequencies ($1 kHz) are spatially profiled and jet velocities exceeding 1 m/s are measured at the exit of the resonators. It has been verified that the resonance frequencies of the device at 50 and 175 kHz can be closely predicted by modeling.
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