According to British scientists, about 300 million operations are performed around the world annually. They cause acute postoperative pain, the management of which is crucial for improving patient outcomes and reducing healthcare costs. Local anesthetic infiltration before closing the surgical incision is a commonly used technique in the operating room. This review focuses on the use of local anesthetic infiltration, 0.25% bupivacaine, into surgical incisions to reduce postoperative pain, as confirmed by an estimate of a reduction in the use of postoperative opioids and a visual analogue scale (VAS). The presented clinical cases and the combined analgesia scheme with infiltration of a local anesthetic into the postoperative wound were used to make it possible to argue about the effectiveness of anesthesia because on the peripheral mechanism of pain. Infiltration analgesia reduced the need for opioids and the time of stay in hospitals. It was concluded that there is a need for further research on methods of delivering anesthetics to postoperative wounds for pain management and improving the quality of treatment.
Протягом останніх двох десятиліть спостерігається тенденція до збільшення використання дитячої регіонарної анестезії. Розширення практики, починаючи від основних нейроаксіальних методів (каудальних та епідуральних блоків) до спинномозкової анестезії, блокад периферичних нервів та блокад сплетень, було підштовхнуто багатьма чинниками, включаючи широкий доступ та використання ультразвукової навігації в практиці лікаря-анестезіолога, краще розуміння токсичності лікарських засобів, визнання придатності блоків та все більш якісні та кількісні свідчення про безпеку [1]. Було проведено декілька великомасштабних проектів для збору пер-
Neuroblastoma is a malignant tumor that develops from the stem cells of the sympathetic ganglia and the adrenal medulla and belongs to the group of neuroendocrine tumors. It is most often localized in the adrenal glands and the retroperitoneal space, less – in sympathetic ganglia of the neck and thoracic cavity. Pain syn-drome is one of the leading manifestations in patients with disease progression. Unlike other patients, a pain syndrome in oncological patients is not a temporary or periodic sensation, it has no physio-logical expediency, it does not have a protective mechanism, but, on the contrary, pain in this group of patients leads to inadaptation, distorted perception of pain and small impulses, most importantly, accompanied by various disorders of the functions of the central nervous system in the patient’s body.
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