In the article authors investigate the problem of readiness of students of the University for the perception of knowledge in the condition of digitalization. Due to the dramatic changing role of the Universities in rapidly developing high-tech environment there is a need for new educational technology, which can provide preparing of young people for life in modern informational society. The purpose of the study is to analyze the readiness of students of the University for the perception of knowledge in life safety in the period of distance education via Internet. Questionnaire survey covered 395 students (245 girls and 150 boys) of Samara University aged from 17 to 24, the research was done with using of Google Drive, section Forms. The research includes the analysis of managing of study and recreation by students, their physical health, changes caused by distance education and students` attitude to different forms of education. We revealed the readiness of students for awareness the necessity to obtain quality and full knowledge, time management that encourages the developing of responsible attitude to personal improvement, adaptation to changing living conditions. Organizers of educational process must provide digital educational platforms, improve and apply new educational learning technology taking into account unequal conditions for students in using the capabilities of the technical equipment. In order to keep all participants healthy it is necessary to take into account time spent for mastering curricula, to use actively digital technology for better messaging information and for checking knowledge when developing new forms and methods of teaching in the condition of digitalization. It is necessary to choose carefully the format of education because of the specificity of subjects. Academic discipline Life Safety includes enough specific training material that demands offline explanation. Especially it is necessary to attend practical classes which develop skills of first aid, behavior algorithms and emergency rescue. The authors conclude: а completely distance education will dramatically lower the quality of teaching, learning, getting necessary skills for students in their future daily and professional life.