This study was conducted to identify and estimate the proportion of patients who had trichomoniasis in relation to gonorrhea and candidiasis in two hundred and twenty (220) women aged between 18 and 55 years from the month of February to June 2005. High vaginal swab (HVS) samples from symptomatic and asymptomatic women in University of Port-Harcourt Teaching Hospital were examined in antenatal, gynecology, family planning and sexually transmitted diseases clinics. Statistical analysis of the data revealed a significant differences (p<0.05) with lower prevalence of gonorrhea co-infected with trichomoniasis among the categories of women examined. Out of two hundred and twenty (220) women examined, 10 (4.5%) were found to be positive for trichomoniasis. The latter percentage was also positive for candidiasis and gonorrhea. From these 10 (4.5%) women, 3 (1.4%) were for gonorrhea in addition to trichomoniasis while 7 (3.2%) out of the 10 (4.5%) examined were positive for both trichomoniasis and candidiasis. Observation showed the most infected women were between ages of eighteen and thirty. In conclusion, this study has shown that co-infection with trichomoniasis and candidiasis is more prevalent in the University of Port Harcourt Teaching Hospital (UPTH).