Background. Currently, there is no generally accepted universal protocol for bowel preparation before colonoscopy in children. Aim. The aim of the study was to compare three different 1-day bowel preparation methods for a pediatric elective colonoscopy in terms of their efficacy, safety, and patient-reported tolerability. Material and Methods. The study was randomized, prospective, and investigator-blinded. All children aged 10 to 18 years consecutively referred to the tertiary pediatric gastroenterology unit were enrolled. The participants were randomized to receive polyethylene glycol 3350 combined with bisacodyl (PEG-bisacodyl group), or polyethylene glycol 4000 with electrolytes (PEG-ELS group), or sodium picosulphate plus magnesium oxide plus citric acid (NaPico+MgCit group). Bowel preparation was assessed according to the Boston Bowel Preparation Scale (BBPS). For patient tolerability and acceptability, questionnaires were obtained. Results. One hundred twenty-three children were allocated to three age- and sex-matched groups. All of the patients completed colonoscopies with visualization of the cecum. There was no difference among the groups for the mean BBPS score. A total of 73 patients (59.3%) experienced minor adverse events. No serious adverse events occurred in any group. Nausea was the only symptom more frequent in the PEG-ELS group compared to the NaPico+MgCit group (p=0.04), and apathy was the only symptom more frequent in PEG-bisacodyl than in the NaPico+MgCit group (p=0.04). All of the patients were able to complete 75% or more of the study protocol, and 85.4% were able to complete the full regimen. The acceptability was the highest in the NaPico+MgCit group with respect to the patient’s grade for palatability, low volume of the solution, and willingness to repeat the same protocol. Conclusion. All bowel cleansing methods show similar efficacy. However, because of the higher tolerability and acceptability profile, the NaPico+MgCit-based regimen appears to be the most proper for colonoscopy preparation in children.
Introduction: Protective vaccinations are an important element of health prophylaxis. Their implementation depends on the parents’ attitudes and their socio-economic situation. Aim: The aim of the study was to evaluate the implementation of vaccinations in children in the Kuyavian-Pomeranian region. Materials and methods: The study included 278 parents of children hospitalised in the Department of Paediatrics, Allergology and Gastroenterology, Antoni Jurasz University Hospital No. 1 in Bydgoszcz. A self-made questionnaire concerning the implementation of compulsory and recommended vaccinations depending on demographical factors and two standardised psychological scales (the Plopa Parental Attitude Scale and the STAI – State-Trait Anxiety Inventory). Results: 93.53% of respondents consider vaccinations necessary. 96.40% of children were vaccinated according to the vaccination schedule. In 3.24%, compulsory vaccination was abandoned at least once, and the vaccination schedule was modified for 67.99% of children. Recommended vaccinations were provided by 47.12% of children, more often from cities, parents with higher education and income and less often with at least three children. Most parents (57.19%) look for information about vaccinations, most often from a doctor and the Internet, less often from posters, leaflets, magazines, and least often from friends and the media. Mothers who are looking for information about vaccination from Internet have lower level of anxiety. Conclusions: The majority of the society implements compulsory vaccinations, and less than half of them are recommended. The implementation is influenced by the financial situation and education of parents. There is a need for individualised education of the society, depending on the social group of recipients.
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