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Results At birth, placental weight was correlated significantly with maternal weight (r=0.21, p=0.031), infant BW (r=0.71, r < 0.001), BMISDS(r=0.589, p<0.001), LSDS (0.567, p<0.001), and HC (r=0.699, p<0.001). During childhood, placental weight was correlated with BMI SDS (r=0.296, p=0.002), HtSDS = (r=0.254, p=0.009). Length SDS at birth was correlated significantly with HtSDS during childhood (r=0.445, p<0.001). Conclusion Placental weight is a good pointer of birth size (weight, length and HC) and may help forecast childhood growth. THE DIFFERENTIAL-DIAGNOSTIC FEATURES OF THELARCHE SYNDROME IN GIRLS

AbstractsMaterial and Methods Thirty macrosomic and 30 sex-matched control newborns were recruited for a retrospective case-control study at the Maghnia Maternity Hospital of Tlemcen Department (Algeria). Results The serum plasma ORAC, albumin, vitamin E, SOD, CAT and GSH-Px levels were significantly decreased in macrosomic than in control newborns, yet no difference was observed after adjustment for weight. Additionally, serum concentrations of malondialdehyde and xanthine oxidase were significantly higher in macrosomic than in controls before adjustment for weight. Moreover, macrosomia was significantly associated with low levels of ORAC (OR = 4.96, Objective The objective of this study was to investigate the influence of maternal weight gain on birth weight of a population of newborns. Patients and MethodsStudy including all patients who delivered in the service of the Maternity Hospital Provincial BENSLIMANE between 1 October 2010 and October 1, 2011. Three groups of patients were formed according to weight gain: less than 8kg, between 8 and 16kg and over 16kg normal. The epidemiological characteristics, obstetric complications and neonatal outcomes were analyzed. The survey is conducted on the basis of a questionnaire, for parturients and obstetric records analysis. Results The mean birth weight was higher in the group "weight gain" ≥ 16 kg "(3782.9±595 g p<0.05) and the rate of newborns weighing more than 3800g (45.5%, p<0.05), unlike those weighing less than 2600g (hypotrophy) whose percentage was higher in the group "weight gain" < 8 kg (6.2% p<0.05), weight gain greater than 16 kg represented a risk factor for dystocia (34.7%). Conclusion An excessive weight gain during pregnancy has deleterious effects on neonatal trophicity. It promotes macrosomia. These data point out the interest to follow the recommendations of weight gain during pregnancy. MARKERS OF THE METABOLIC SYNDROME AND PHYSICAL ACTIVITY IN TEENAGE CHILDREN BORN PRETERM Background and Aims The worldwide increase in the MetabolicSyndrome is associated with adverse health outcomes and significant healthcare costs. Early life exposures are key factors in determining later health. Children born preterm appear to be at higher risks of developing insulin resistance. We aimed to determine the prevalence of novel metabolic biomarkers in a cohort of teenage children who were born preterm (< =34 weeks gestation) and correlate these with physical activity. CLINICAL-LABORATORY PECULIARITIES IN CHILDREN WITH OBESITY AND METABOLIC SYNDROME

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