Total body composition by dual energy X-ray absorptiometry (DEXA) can be used as an specific method of measuring body composition to identify the individual risk of metabolic complications in children.Objective: To investigate serum leptin level and its relationship with bone mineral density in obese children. Materials and methods:91 children with obesity (male / female = 52/39, mean age 12,81 ± 0,5 years) were involved. DEXA was used to determine bone mineral density and body composition. BMI were average 95 percentile for age and sex. Serum leptin was measured using ELISA by "DRG Diagnostics" (USA). All the data were performed non-parametric (ANOVA, test of Mann-Whitney U) and parametric (t-Student criterion) methods. Results:The mean BMI m/f (29,7 ± 0,68/28,3 ± 0,52 kg/m 2 ) (p = 0,05).A significant gender differences were revealed in "total body" criteria, more pronounced in girls. Decrease of the mineral density by Z-score(-2,5 Standard Deviation) were found in 20% of boys and 22% of girls at puberty age. A correlation bone mineral density and lean mass were observed in prepubertal (r = 0,9) and early pubertal (r = 0,79) boys groups. This correlations wasn't noted in girls. Serum leptin level was positively correlated with mineral density (m / f) prepubertal (r = 0,3 / 0,46), early pubertal (r = 0,32 / 0,49), pubertal (r = 0,4 / 0,58) groups, more expressed in girls (p> 0,01).Conclusions: Serum leptin level was positively correlated with mineral density. A lean mass was significantly correlated with mineral density in boys.

Results At birth, placental weight was correlated significantly with maternal weight (r=0.21, p=0.031), infant BW (r=0.71, r < 0.001), BMISDS(r=0.589, p<0.001), LSDS (0.567, p<0.001), and HC (r=0.699, p<0.001). During childhood, placental weight was correlated with BMI SDS (r=0.296, p=0.002), HtSDS = (r=0.254, p=0.009). Length SDS at birth was correlated significantly with HtSDS during childhood (r=0.445, p<0.001). Conclusion Placental weight is a good pointer of birth size (weight, length and HC) and may help forecast childhood growth. THE DIFFERENTIAL-DIAGNOSTIC FEATURES OF THELARCHE SYNDROME IN GIRLS

AbstractsMaterial and Methods Thirty macrosomic and 30 sex-matched control newborns were recruited for a retrospective case-control study at the Maghnia Maternity Hospital of Tlemcen Department (Algeria). Results The serum plasma ORAC, albumin, vitamin E, SOD, CAT and GSH-Px levels were significantly decreased in macrosomic than in control newborns, yet no difference was observed after adjustment for weight. Additionally, serum concentrations of malondialdehyde and xanthine oxidase were significantly higher in macrosomic than in controls before adjustment for weight. Moreover, macrosomia was significantly associated with low levels of ORAC (OR = 4.96, Objective The objective of this study was to investigate the influence of maternal weight gain on birth weight of a population of newborns. Patients and MethodsStudy including all patients who delivered in the service of the Maternity Hospital Provincial BENSLIMANE between 1 October 2010 and October 1, 2011. Three groups of patients were formed according to weight gain: less than 8kg, between 8 and 16kg and over 16kg normal. The epidemiological characteristics, obstetric complications and neonatal outcomes were analyzed. The survey is conducted on the basis of a questionnaire, for parturients and obstetric records analysis. Results The mean birth weight was higher in the group "weight gain" ≥ 16 kg "(3782.9±595 g p<0.05) and the rate of newborns weighing more than 3800g (45.5%, p<0.05), unlike those weighing less than 2600g (hypotrophy) whose percentage was higher in the group "weight gain" < 8 kg (6.2% p<0.05), weight gain greater than 16 kg represented a risk factor for dystocia (34.7%). Conclusion An excessive weight gain during pregnancy has deleterious effects on neonatal trophicity. It promotes macrosomia. These data point out the interest to follow the recommendations of weight gain during pregnancy. MARKERS OF THE METABOLIC SYNDROME AND PHYSICAL ACTIVITY IN TEENAGE CHILDREN BORN PRETERM Background and Aims The worldwide increase in the MetabolicSyndrome is associated with adverse health outcomes and significant healthcare costs. Early life exposures are key factors in determining later health. Children born preterm appear to be at higher risks of developing insulin resistance. We aimed to determine the prevalence of novel metabolic biomarkers in a cohort of teenage children who were born preterm (< =34 weeks gestation) and correlate these with physical activity. CLINICAL-LABORATORY PECULIARITIES IN CHILDREN WITH OBESITY AND METABOLIC SYNDROME

Results At birth, placental weight was correlated significantly with maternal weight (r=0.21, p=0.031), infant BW (r=0.71, r < 0.001), BMISDS(r=0.589, p<0.001), LSDS (0.567, p<0.001), and HC (r=0.699, p<0.001). During childhood, placental weight was correlated with BMI SDS (r=0.296, p=0.002), HtSDS = (r=0.254, p=0.009). Length SDS at birth was correlated significantly with HtSDS during childhood (r=0.445, p<0.001). Conclusion Placental weight is a good pointer of birth size (weight, length and HC) and may help forecast childhood growth. THE DIFFERENTIAL-DIAGNOSTIC FEATURES OF THELARCHE SYNDROME IN GIRLS

Abstracts nursing mothers regarding exclusive breast feeding, and a mere 36% counselled mothers on possible obstacles and how to overcome them. Conclusions Despite generally high knowledge scores in our study population, as well as positive attitudes, actual practices need to be improved. Further studies to assess barriers to optimal counselling practices need to be performed. Background and Aims It is clear that measuring physical activity (PA) in children is a major challenge and Accelerometers are useful instruments for this reason. The aims of this study were to measure PA pattern of student by accelerometer and to evaluate differences by gender and age. Methods The sample for present study comprised 270 children (boys n=119 and girls n=151), aged 6 to 9 years old. The GT3X activity monitor was used as an objective measure of daily PA. Each student was scheduled to wear the accelerometer during the week of monitoring. Results The mean overall activity was higher in boys than in girls, but this difference was significant only on weekdays (P<0.05). Overall PA was significantly correlated with age both in whole week (P<0.01) and weekends (P<0.001). Conclusion Our findings are important for a better understanding of PA pattern in students of Tehran city, which is essential for education and health promotion. The results show that boys are more active than girls. PHYSICAL