The PFG NMR technique is applied to investigate the intracrystalline diffusion of methane and n-butane molecules in MFI-type zeolites at several temperatures (from 123 up to 383 K) and over a wide range of diffusion times (from 2 to 35 ms). The intracrystalline self-diffusion coefficients of the guest molecules recorded at low temperatures were observed to decrease with increasing root-mean-square displacements. The comparison of the experimental results with the results of the Monte Carlo simulations of diffusion allowed us to rule out the restriction of diffusion by crystal boundaries as a possible explanation of the observed dependencies of the diffusivities on the root-mean-square displacement. These dependencies are tentatively attributed to the existence of intracrystalline transport barriers in MFI-type crystals. The intersections between the elementary building blocks of the crystals and/or intergrowth sections of MFI crystals are suggested as the possible candidates for the transport barriers.

Interference microscopy is applied to carry out investigations of the influence of the regular intergrowth effects commonly observed in large silicalite-1 crystals on adsorption/desorption of isobutane. The intracrystalline concentration profiles measured by interference microscopy during adsorption of isobutane are compared with those simulated using the Monte Carlo method. The comparison of the simulated and the measured profiles allows the possibility that the uptake of isobutane from the gas phase into silicalite-1 crystals proceeds through the internal interfaces separating the intergrowth sections of the crystals to be ruled out. The diffusion coefficient of isobutane obtained by comparing the simulated and the measured concentration profiles is found to be in agreement with the previously reported diffusivities of isobutane in silicalite-1.

Pretreatment tumor ADC does not predict treatment response for patients with LABC undergoing NACT. Furthermore, ADC increase observed mid-way in the course of NACT does not correlate with tumor volume changes.

A systematic study using segmented MR images was undertaken. To achieve an acceptable accuracy in the CTV dose, the MR images should be segmented into bone and water equivalent tissue. Still, significant dose deviation for the organs at risk may be present. As tissue segmentation in real MR images is introduced, segmentation errors and errors that stem from geometrical non-linearities may further reduce the accuracy.