For a smooth projective scheme X over a ring R on which p is nilpotent that meets some general assumptions we prove that the crystalline cohomology is equipped with the structure of a higher display which is a relative version of Fontaine's strongly divisible lattices. Frobenius-divisibility is induced by the Nygaard filtration on the relative de Rham-Witt complex. For a nilpotent PD-thickening S/R we also consider the associated relative display and can describe it explicitly by a relative version of the Nygaard filtration on the de Rham-Witt complex associated to a lifting of X over S. We prove that there is a crystal of relative displays if moreover the mod p reduction of X has a smooth and versal deformation space.

In this paper we present an interesting case of acute kidney injury and severe metabolic alkalosis in a patient with a history of heavy heroin abuse. Urine microscopy showed numerous broomstick-like crystals. These crystals are also identified in light and electron microscopy. We hypothesize that heroin crystalizes in an alkaline pH, resulting in tubular obstruction and acute kidney injury. Management is mainly supportive as there is no known specific therapy for this condition. This paper highlights the utility of urine microscopy in diagnosing the etiology of acute kidney injury and proposes a novel disease called heroin crystal nephropathy.

The transcriptional activator RtcR and the RNA repair proteins whose expression it regulates, RtcA and RtcB, are widely conserved in Proteobacteria . In Salmonella Typhimurium 14028s, genotoxic stress activates RtcR to direct RpoN-dependent expression of the rsr-yrlBA-rtcBA operon.