Community pharmacists in Lagos had poor knowledge about pharmacovigilance. Reporting rate was also poor. There is an urgent need for educational programs to train pharmacists about pharmacovigilance and ADR reporting.
Various types of AEs were seen and documented during the CEM programme. The findings suggested that the AA/AL monitored during this programme was generally safe and remarkably well tolerated among the Nigerian populations.
The suitability of three different types of extraction kinetic models (one-step, two-step and threestep models) for neem oil was investigated in this study. Solvent extraction using n-hexane at temperatures range between 303K and 323 K; 360minutes of extraction time were experimented and the oil yield calculated. The three models were fitted to the experimental data obtained. The oil yield increased from 31.80 % to 41% at 303K and 323 K, respectively and the equilibrium was reached at 300 minutes. The saturation extraction capacity (C s) increased from 35.0631 gL-1 to 42.9698 gL-1 303K and 323 K, respectively for one step model and the R 2 ranged between 0.9874 and 0.9998. The washing mass transfer coefficient (C e W) of oil yields at equilibrium accounts for about 60% of the extraction in the two-step model and the R 2 ranged between 0.9840 and 0.9960. The first coefficient of diffusion (w e d1) in the three-step model had is higher value than the second (w e d2) and R 2 ranged between 0.9920 and 0.9980. The three-step model best fitted the experimental data.
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