It has been documented that lead can cause a wide range of adverse reproductive outcomes. In men, lead can reduce the libido and affect spermatogenesis reducing the quality of sperm. Other effects in exposed men include disturbance of prostatic function and damage in serum testosterone. In pregnant women, lead can cross the placenta and impair the development of the fetus. Therefore, exposed women are at risk of suffering spontaneous abortion, premature delivery, gestational diabetes mellitus, pregnancy hypertension, preeclampsia, premature rupture of membranes, intrauterine growth restriction, low weight birth, and other pregnancy complications. In both men and women, lead has been associated with infertility. Harmful effects of this heavy metal have been observed even at low levels of exposure. Thus, exposure to lead remains a public health problem, especially for reproductive health. Some strategies should be considered to prevent harmful effects of lead on both male and female reproductive systems.

Objectives To examine the relationship between occupation and blood lead levels in pregnant women of Durango, Mexico. Method A cross sectional study was conducted with 299 pregnant women. Information on occupation, risk factors and sociodemographic data was collected by means of a structured questionnaire. Blood lead concentration was tested by graphite furnace spectrometry. Women were divided into three groups according to occupation: working in places with potential source of lead exposure (exposed group), working in places without lead exposure (control group I), and non-working women (control group II). The X 2 test was used to assess statistical differences between the groups, and one way ANOVA was applied for comparisons. Logistic regression was performed using blood lead < 5 mg/dL or ≥ 5 mg/dL as dependent variable, and ajdusted for jurisdiction, income, gestational age, and abortions. Results Only 24(8%) women worked in places with potential source of lead exposure, 47(15.7%) worked in other places, and 228(76.3%) did not have a remunerated job. Mean blood lead concentration in the study sample was 2.79 mg/dL. However, blood lead ≥ 5 mg/dL accounted for 25% of exposed women, 2.1% of control group I, and 6% of control group II (X 2 = 13.04; p .001). Mean blood lead level was 4.24 mg/dL in the exposed group, 2.31 mg/dL in the control group I, and 2.74 mg/ dL in the control group II; those differences were statistically significant (0.001). Logistic regression confirmed that blood lead ≥ 5 mg/dL is associated with occupational exposure (p = 0.036). Conclusions Our findings suggest that surveillance for occupational exposure to prevent health damages during pregnancy is needed. 0243 SCREENING AND DISABILITY PREVENTION FOR MUSCULOSKELETAL DISORDERS OF HIGH-TECH INDUSTRY WORKERS IN TAIWANYa-Yuan Hsu. Institute of Occupational Safety and Health, Taipei, Taiwan 10. 1136/oemed-2014-102362.287 Objectives In Taiwan, 40-60% of the working population is affected by musculoskelet al disorders (MSD). MSD may lead to reduced productivity, decreased work ability, and even disability. The aim of this study was to describe the effects about occupational health medical team preventing and management of MSD. Method The design was prospective study describing the hightech industry workers screening and disability prevention for MSD. The quantitative analysis of the questionnaire was conducted through descriptive statistics and pair-t test in order to indicate the direction and relationship between the two sets of occupational health medical team intervention program. Results Of the 386 high-tech industry workers who completed the questionnaire. The use of pair-t test comparing two months of occupational health medical program, individual symptom scores significantly decreased 1.99 points to 6.12 points. The degree of functional subjects increased from 57% to 74%, a significant improvement. Work ability index before treatment was 38.49 to 39.36 points after treatment improved, particularly in the self-evaluation and self-ab...

Method Cross-sectional study that included 72 workers of the Mexico-Puebla Highway cabins (guards); 60 cashiers and 12 workers in charge of the shift, in which socio-demographic, clinical and occupational variables were explored; haemoglobin (Hb), hematocrit (HCT) and carboxyhemoglobin (COHb) was determined in their blood, and it was applied the CONSB for CO. The workers who are in charge of the full shift integrated the less exposed to CO group, while the cashiers would shape the greater exposure group. Results In 49 workers, Hb: 18.1 ± 1.9 mg/dL and Hcto: 55.3 ± 8.7 without significant differences in the presence or absence of erythrocytosis between exposure groups (p = 0.82). In the neuropsychological tests of 72 workers, greater alteration was identified in the exposed group, only in the test of symbol and digits (p = 0.001), trail making B (p = 0.002), and test of digits (p = 0.003); the test of building with blocks resulted borderline (p = 0.07). In all tests except in the test of learning of Rey, the non-exposed showed better performance. Conclusions Despite what has been achieved, it is important to follow up the erythrocytosis and the neuropsychological effects on all workers, in addition to start treatment to prevent complications. The perception of innocuousness of chronic exposure to CO in these workersmust avoid. Objectives To explore the prevalence of obesity and risk of metabolic complications among workers of a harness plant in Durango, Mexico. Method A croos-sectional study was conducted on 300 workers. Measurements of body mass index (BMI) and waist hip ratio (WHR) were obtained. BMI (m/kg 2 ) was classified into underweight (<18.5), normal range (18.5-24.9), pre-obese (25.0-29.9), obese class I (30.0-34.9), obese class II (35.0-39.9), and obese class III (≥40.0). Risk of metabolic complications (RMC) was considered high when WHR > 0.85 for women, and > 0.95 for men; and moderated between 0.80-0.85 for women and 0.90-0.95 for men. Analysis of variance (ANOVA) was applied for continuos variables, and 2 test for categorical variables. Results The mean age (±SD) of the subjects was 28.7 (±8.9) yrs. In the sample, 51.7% were male. According to the BMI, 47.3% of participants were in the normal range, 35.3% preobese, and 15.7% showed obesity. According to the WHR, 30% were at high risk, and 28.6% at moderate risk for developing metabolic complications. The RMC (high and moderate) was significant more prevalent in women than in men, 77.5% vs 49.3%, (p < 0.0001). ANOVA yielded significant variation in obesity according to age (p < 0.001). Post hoc Tukey test showed differences of obese class II with normal range (p = 0.007) and underweight (p = 0.0169). Conclusions The prevalence of obesity and RMC are quite high in studied population. The risk is higher among women and increases with age. Objectives This study aims to identify the presence of burnout in nursing workers of a intensive care skilled in children with heart disease. Method This is an exploratory, transversal and quantitative study with 92 ...