Objectives The aim of this study was to describe the process of regeneration of damaged salivary glands due to ionizing radiations by bone marrow mesenchymal stem cells (BM-MSCs) transplantation that have been given hypoxic preconditioning with 1% O2 concentration. Materials and Methods Stem cell culture was performed under normoxic (O2: 21%) and hypoxic conditions by incubating the cells for 48 hours in a low oxygen tension chamber consisting of 95% N2, 5% CO2, and 1% O2. Thirty male Wistar rats were divided into four groups: two groups of control and two groups of treatment. A single dose of 15 Gy radiation was provided to the ventral region of the neck in all treatment groups, damaging the salivary glands. BM-MSCs transplantation was performed in the treatment groups for normoxia and hypoxia 24-hour postradiation. Statistical Analysis Statistical analysis was done using normality test, followed by MANOVA test (p < 0.05). Results There was a significant difference in the expression of binding SDF1-CXCR4, Bcl-2 (p < 0.05) and also the activity of the enzyme α-amylase in all groups of hypoxia. Conclusion BM-MSCs transplantation with hypoxic precondition increases the expression of binding SDF1-CXCR4, Bcl-2 that contributes to cell migration, cell survival, and cell differentiation.
Objectives: This research is aimed do find out the differences of interprocessus distances between males and females using panoramic radiographs. Materials and Methods: This research is using observational analytic with cross sectional study design. Secondary data was taken from 96 panoramic radiographs consisting of 48 males and 48 females, from RSKGM-P Universitas Airlangga. Measurements were carried out using ImageJ Software by 3 observers. The measurement results were then analyzed by independent t-test and the inter-measuring reliability was tested using the Intraclass Correlation Coefficient (ICC) on IBM SPSS software. Results: The result showed that the significance value (2-tailed) of interprocessus distances measurement on males and females was <0.05 in both regions. Reliability test of inter-observer using ICC obtained the overall measurement results was more than 0.75 which means excellent reliability. Conclusion: There was a significant difference between the interprocessus distances on males and females as measured by panoramic radiographs.
Objectives: Panoramic radiographs are used as a diagnostic tool adjunctive to oral examinations, treatment plans, and evaluation of treatment outcomes. This study was aimed to determine the distribution of Dense Bone Island (DBI) in the jaws through panoramic radiography based on gender and age. Materials and Methods: The method used for this research is descriptive-observational. The research data used is secondary data with a total of 422 panoramic radiographic data of RSKGMP Airlangga University patients. Results: From a study of 422 secondary data found 253 (60%) patients with Dense Bone Island in the jaw, more commonly found in female, which is 162 (38.4%) in female patients and 91 (21.5%) in male patients. It was also found mostly in the age range of 17–25 years. Conclusion: Dense Bone Island was found more in female than in male. It was also found to be more common in patients aged 17–25 years.
Radiologi Kedokteran Gigi merupakan salah satu bidang ilmu yang memiliki peran penting di bidang kedokteran gigi. Salah satu teknik radiografi yang sering digunakan adalah radiografi periapical. Untuk pembuatan radiografi periapikal guna perawatan saluran akar atau kondisi lain yang memerlukan kondisi tanpa superimposisi maka radiografi periapikal dengan gambaran dua dimensi tidak selalu dapat memenuhi tujuan pemeriksaan yang diinginkan oleh dokter gigi. Saluran akar bukal dan lingual seringkali tampak superimposisi (tumpang tindih) satu sama lain pada radiografi periapikal dan memerlukan pemisahan agar dapat diidentifikasi secara tepat. Salah satu metode yang dapat digunakan adalah adalah Buccal Object Rule atau Clark’s Rule. Banyak permintaan dokter gigi untuk memperoleh radiograf yang gambarannya tidak tumpang tindih, namun belum banyak radiografer yang menguasai teknik atau metode ini. Metode dari kegiatan ini yaitu dengan pemberian materi dilanjutkan dengan pelatihan melalui video tutorial secara daring. Hasil yang dicapai meningkatnya kemampuan peserta di buktikan dengan rerata hasil post test (8,05) meningkat dari hasil pre test (5,72).
Objectives: The principle of measurement using the TCI (Tooth Coronal Index) method is to compare the pulp chamber height with a person's chronological age based on the formation of secondary dentin. The purpose of this study is to estimate age based on pulp chamber height in lower canines using periapical radiographs with TCI measurement. Materials and Methods: This study is an observational analytic study using 42 samples of periapical radiographs with the parallel technique of the lower canines. Samples were measured for CH and CPCH heights to determine TCI values and then linear regression was made to determine their biological age. Finally, the difference between biological and chronological age is calculated to determine the approximate age. Results: The mean difference between chronological age and biological age was ± 5.05 years and an average biological age of 29.38 years. Conclusion: TCI method based on pulp chamber height in lower canines using periapical radiographs can be used to estimate age with the difference between chronological age and biological age of ±5.05 years.
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