The endoscopic endonasal transsphenoidal approach is a widely-used method for the surgical treatment of pituitary adenomas. We aimed to evaluate the results of endoscopic surgery by comparing preoperative classification methods and investigating their relationship with postoperative resection and remission rates and complications. Methods : We retrospectively reviewed the medical records of 236 patients (118 males) who underwent surgery for pituitary adenomas. Preoperative Knosp classification, tumor size (TS), suprasellar extension (SSE), postoperative resection and remission rates, and complications were evaluated. Results : The follow-up period was 3 months to 6 years. The patients' ages ranged between 16 and 84 years. Endocrinologically, 114 patients (48.3%) had functional adenoma (FA), and 122 patients (51.7%) had non-functional adenoma (NFA). Among the FA group, 92 (80.7%) showed remission. A statistically significant difference was found between patients with and without remission in terms of the Knosp, TS, and SSE classifications (p<0.01). Knosp, TS, and SSE classification grades were found to be correlated with the resection rates (p<0.01). Meningitis was seen in seven patients (3.0%), diabetes insipidus in 16 (6.9%; permanently in two [0.9%]), and rhinorrhea in 19 (8.1%). Thirty-six patients (15.3%) developed pituitary insufficiency and received hormone replacement therapy. Conclusion :The resection categories and remission rates of FAs were directly proportional to the adenoma sizes and Knosp grades, while the degree of suprasellar growth further complicated resection and remission rates. Adenoma sizes less than 2 cm and SSEs less than 1 cm are associated with favorable remission and resection rates.

Objective: This study aimed to examine the parameters thought to reduce the mortality of patients with epidural-subdural hemorrhage, basal ganglia hemorrhage, edema with compression effect due to intracerebral ischemic infarction, and hemorrhage from infarcts and to find significant relationships accordingly. Material and Methods:The demographic and clinical characteristics of patients, pre-operative Glasgow Coma scale (GCS), duration of the operation after the development of the first event, length of stay in intensive care units (ICUs), infection and antibiotic therapy rates developed during their hospitalization, and long-term follow-up were recorded. The survival of the patients were compared statistically. Results:In 38 patients with GCS less than 10 points, pre-operative GCS, length of stay in ICUs, duration of mechanical ventilator support, infection, and need for antibiotic therapy were examined. All patients were divided into four groups; subdural-epidural hematoma, intracerebral hematoma, intracerebral ischemic infarction, and post-infarction hemorrhage groups. The relationship between their data and mortality were studied. The pre-operative GCS scores in the four groups were 6.16, 6.73, 7.13, and 6.28, respectively. The pre-operative GCS in these four dead groups were 5, 6.6, 7, and 6, respectively. There was no difference between the variables and mortality. Conclusion:No correlation was found between all clinical data and survival rates. The benefits of an early surgery shown in previous studies were not associated with mortality in this study. Studies with larger case series are needed for more significant relationships.