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SUMMARY OBJECTIVE: The aim of this study was to evaluate the prognostic value of whole blood parameters, systemic inflammatory indices, and systemic inflammatory markers in pregnant women with COVID-19. METHODS: In this cross-sectional study, the demographic, clinical, and laboratory data (i.e., whole blood parameters, C-reactive protein, procalcitonin, ferritin, and D-dimer) of 464 pregnant women with COVID-19 who attended a tertiary hospital between January and April 2021 were reviewed. Systemic inflammatory indices (i.e., neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, platelet/neutrophil ratio, and systemic immune inflammation index) were calculated. Asymptomatic and mildly symptomatic pregnant women were classified as Group 1 (n=413), and those with severe disease were classified as Group 2 (n=51). RESULTS: Lymphocyte count and lymphocyte percentage in whole blood parameters were significantly lower (p<0.05), and C-reactive protein, ferritin, and procalcitonin values were higher in Group 2 (p<0.05). Systemic inflammatory indices [neutrophil/lymphocyte ratio (4.7±2.9 (1.1–21.2) vs 7.5±4.7 (2.13–23.2)), platelet/lymphocyte ratio (191.1±104.3 (53.0–807.1) vs 269.5±118.9 (105.0–756.0)), systemic immune inflammation index (1,000±663 (209–5,231) vs 1,630±1,314 (345–7,006))] were found statistically significantly higher in severe disease group (p<0.001). CONCLUSION: Evidence in this study indicates that neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and systemic immune inflammation index at first admission are simple, rapid, and inexpensive indices in predicting the prognosis of COVID-19 in pregnant women.

The aim of this study is to investigate the anxiety levels of low-risk term pregnant women hospitalized for labor during the SARS-CoV-2 (COVID-19) pandemic. Materials and Methods:This cross-sectional survey study includes 200 low-risk term pregnant women hospitalized for delivery. Sociodemographic and obstetric data were collected. Anxiety levels of pregnant women were examined using Spielberger State-Trait Anxiety Inventory questionnaire form on admission. Total scores greater than 50 were classified as pathological levels of anxiety. Results:The mean trait score was 36.99±10.08 and the mean state score was 41.03±8.89, and the difference between these two scores was statistically significant. State and trait scores were higher in pregnant women who had contact with COVID-19 infected people than those who had not. There was a significant positive correlation between state and trait scores. The history of contact with COVID-19 infected person and the presence of pathological trait anxity were determined as significant factors for the presence of pathological state anxiety related to COVID-19 pandemic. Conclusion:Pregnant women with history of contact with COVID-19 infected person or with pathological trait anxiety have higher state anxiety during COVID-19 outbreak. It is important to identify women with high risk of developing anxiety in order to provide early psychological interventions.

Aim: To investigate the clinical course of COVID-19 in different trimesters of pregnancy by evaluating the demographic, clinical and laboratory data of pregnant women who applied to the Emergency Service. Materials and method: Cases were examined in 3 groups as asymptomatic, mild symptomatic and severe disease according to symptoms and oxygen saturation. High levels of CRP, ferritin, D-dimer and lymphopenia in blood tests were considered as poor prognostic factors. Results: Of 678 pregnant women with COVİD-19 , 118 (17.4%) were in the first trimester, 261 (38.5%) were in the second trimester and 299 (44.1%) were in the third trimester. A total of 257 (37.9%) COVID-19 (+) pregnant women were hospitalized and 120 of them were due to COVID-19 infection without any obstetric indication. Severe disease was detected in 57 (8.4%) of the cases; 29 of them (50.9%) were in the 2nd trimester and 26 (45.6%) were in the 3rd trimester. The incidence of severe disease was statistically significantly higher in the later weeks of pregnancy compared to the first trimester (p=0.004). When the distribution of the poor prognostic laboratory criteria according to trimesters was examined, 22.9% of pregnant women with COVID-19 had at least one poor prognostic laboratory criterion in the first trimester, while this rate was 41.7% and 63.9% in the second and third trimesters, respectively (p