The clinicopathological data of 1146 enucleated eyes obtained from 1146 patients (485 females and 661 males; mean age 57*4 (SD 21.6) years) between 1980

The LDF parameters, measured in the ONH, did not indicate an abnormal Fonh regulation in response to an increase of the PPm in either normal subjects or NTG patients. The maintenance of constant blood flow is achieved by an increase in local vascular resistance. Our data show a greater percent increase in vascular resistance in the NTG patients compared to the normal subjects for a similar percent increase in PPm in both groups during squatting. This suggests some alteration of the vessel tone regulatory mechanisms in NTG patients.

Between 1981 and 1994, the detection of specific antibodies against Toxoplasma gondii was performed simultaneously in serum and aqueous humor from 90 patients, and the Witmer-Desmonts coefficient measuring the relative concentration of antibodies produced locally was calculated to confirm the clinical diagnosis of ocular toxoplasmosis. Thirty-seven results were positive (41.1%), 12 uncertain (13.3%) and 41 negative (45.6%). These results are compared with the data obtained by the polymerase chain reaction for the genomic detection of an infectious agent in the aqueous humor that have recently been published.

After having been the subject of several studies during the first half of the 20th century, the anatomical and morphological measurements of the ocular rectus muscles have recently been reinvestigated (e.g. L. Apt). At the Anatomy Institute in Geneva, similar measurements were performed on 25 human orbits as well as the depth of the subtenon space. The results show a large variation from one individual to another, although the "Tillaux spiral" was always respected. We have also shown that the ratio of the arc between each pair of opposed rectus muscles is a constant equal to 1 (0.997 +/- SD = 0.031). The subtenon space was defined morphometrically and confirmed histologically. All these measurements are important for practical aspects involved in the surgery of strabismus.

The purpose of this study was to examine the refractive status, orthoptic status and visual perception in a group of preterm and another of full-term children with cerebral palsy, in order to investigate whether prematurity has an effect on the development of refractive errors and binocular disorders. A hundred school-aged children, 70 preterm and 30 full-term, with congenital cerebral palsy were examined. Differences for hypermetropia, myopia, and emmetropia were not statistically significant between the 2 groups. Astigmatism was significantly increased in the preterm group. The orthoptic status was similar for both groups. Visual perception was markedly reduced in both groups, but the differences were not significant. In conclusion, children with cerebral palsy have impaired visual skills, leading to reading difficulties. The presence of prematurity does not appear to represent an additional risk factor for the development of refractive errors and binocular disorders.