Ahrgnnli, C.; Creaasri. A.; Sewn, A.; Beolchini, P . E.; Borbaini. S. and Ginnotri, G. A,:Vox Sang. 4: 261-211 (1959)

SUMMARYA statistical analysis has been made on the clinico-anamnestic information concerning 432 mongol propositi, taking into particular consideration the age of parents, the order of birth and the reproductive features observed in the families of the propositi. The Authors furthermore examine the possibility of making an eugenical counseling concerning the probability of a new occurrence of the syndrome.

No abstract

A genetic polymorphism of human serum @-lipoproteins (the Ag system) was first reported by ALLISON and BLUMBERG [l] in 1961.This system was detected in Ouchterlony immuno-diffusion using an iso-antibody from a patient who had received multiple blood transfusions [l, 21. Recently it has been demonstrated that the Ag(x) and Ag(y) factors are controlled by allelic genes [lo, 12, 141. Antibodies directed against other factors of the same system (Ag(a,), Ag(z) and Ag(t)) have been found in the sera of transfused patients [6, 111, especially from children with thalassemia major [li, 7, 151.