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The magnetic targeted drug delivery system of Avil´es, Ebner and Ritter, which uses high gradient magnetic separation (HGMS) is considered. In that model large ferromagnetic particles are used as seeds to aid collection of multiple domain nanoparticles (radius ≈ 200 nm).Here, in contrast, single domain magnetic nanoparticles (radius in 20-100 nm) are considered and the Langevin function is used to describe the magnetization. The magnetic targeted drug delivery system of Avilés, Ebner and Ritter, which uses

The implant assisted magnetic targeted drug delivery system of Avilés, Ebner and Ritter is considered both experimentally (in vitro) and theoretically. The results of a 2D mathematical model are compared with 3D experimental results for a magnetizable wire stent. In this experiment a ferromagnetic, coiled wire stent is implanted to aid collection of particles which consist of single domain magnetic nanoparticles (radius ≈ 10 nm). In order to model the agglomeration of particles known to occur in this system, the magnetic dipole-dipole and hy- A c c e p t e d m a n u s c r i p t PACS: 47.63.mh, 87.85.gf

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