corresponding to 98% live time for collection. We set a limit on the core-collapse supernova rate out to a distance of 13.4 kpc to be less than 0.69 supernovae per year at 90% C.L.

The first formal qualification of safety biomarkers for regulatory decision making marks a milestone in the application of biomarkers to drug development. Following submission of drug toxicity studies and analyses of biomarker performance to the Food and Drug Administration (FDA) and European Medicines Agency (EMEA) by the Predictive Safety Testing Consortium's (PSTC) Nephrotoxicity Working Group, seven renal safety biomarkers have been qualified for limited use in nonclinical and clinical drug development to help guide safety assessments. This was a pilot process, and the experience gained will both facilitate better understanding of how the qualification process will probably evolve and clarify the minimal requirements necessary to evaluate the performance of biomarkers of organ injury within specific contexts.

A mistake in the computer program performing the power law fit of the numerical computation of the hadron attenuation ratio R M has been detected. The mistake affects all fits which include the Xe nucleus. Below we present corrected results for table 2 and Figs. 8-10.Based on the corrected calculation we revise our conclusion in ref. [1]. The A 2/3 power law for 1 − R M in the absorption model remains also after including the Xe nucleus in the (c,α) fit.

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Using a high-statistics, high-purity sample of νµ-induced charged current, charged pion events in mineral oil (CH2), MiniBooNE reports a collection of interaction cross sections for this process. This includes measurements of the CCπ + cross section as a function of neutrino energy, as well as flux-averaged single-and double-differential cross sections of the energy and direction of both the final-state muon and pion. In addition, each of the single-differential cross sections are extracted as a function of neutrino energy to decouple the shape of the MiniBooNE energy spectrum from the results. In many cases, these cross sections are the first time such quantities have been measured on a nuclear target and in the 1 GeV energy range.