The aim of this study was to report the analysis of a single-center experience with single-balloon enteroscopy (SBE). A retrospective analysis of patients with small-bowel disorder who underwent SBE procedure from February 2011 to February 2013 was carried out. A total of 40 patients underwent 48 SBE procedures. Antegrade and retrograde approaches were used in 68.8 % and 31.2 % of subjects, respectively. The main indications were obscure gastrointestinal bleeding (n = 28), chronic diarrhea (n = 6), and chronic abdominal pain (n = 6). Average (SD) insertion length by antegrade approach was 150.6 (31.4) cm (range 90-210 cm) beyond the duodenojejunal flexure and by retrograde approach was 106.6 (29.4) cm (range 40-140 cm) proximal to the ileocecal junction. Average procedure time for antegrade approach was 46.3 (9.0) min (range 25-60 min) and for retrograde approach was 61.3 (12.8) min (range 45-90 min). Panendoscopy was not possible in any of the eight patients in whom antegrade and retrograde approaches were performed. Overall diagnostic yield was 55 % and therapeutic procedures were done in 20 % of patients. There were no significant complications. SBE is a safe and effective method to diagnose patients with small-bowel disease and provides a useful tool for intervention.

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