Examination of pancreases from a series of 207 autopsies of adults without either clinical or autopsy evidence of insular hyperfunction showed minimal nesidioblastosis in 36.7%. Ductulo-insular complexes, together with insular cells among the acini, were found in 10.6% of the biopsy specimens. Nesidioblastosis was more frequent in men (61.8%), and the oldest individual was an 84-year-old man. Ductulo-insular complexes and the aggregations of insular cells in the exocrine parenchyma develop asynchronously and may have been initiated by different stimuli. This series did not explain the possible causative factors.

Chronic herpetic laryngitis, with or without involvement of the oropharynx, is uncommon. We describe a case that was initially diagnosed and treated as squamous cell carcinoma. The subsequent course of the disease, review of the histologic material, and additional laboratory investigation suggested that the lesion was of viral origin and probably was caused by herpes simplex.

Isolated necrotizing granulomatous vasculitis of the spermatic cord has not been described during the last 20 years. We report clinical, laboratory and histopathological features of an instance of contralaterally recurrent lesions of this type in a young photographic laboratory technician. Although to date the disease is considered to be isolated, it may well be a systemic one without yet obvious signs.

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