Aim:This study was planned to reveal the clinical signs and biochemical alterations in pregnancy toxemic goats.Materials and Methods:Blood samples were collected from 20 healthy pregnant and 45 pregnancy toxemic goats and analyzed biochemically.Results:The most significant clinical findings were observed in naturally affected goats with pregnancy toxemia included anorexia, recumbency, lethargy, opisthotonos, dropped head, periodic convulsion, sweetish fruity odor from breath, apparent blindness, bloat, grinding of teeth, and frothy salivation. In this study, the level of serum glutamic-oxaloacetic transaminase (SGOT) (84.23±1.44 IU/L), serum glutamic pyruvic transaminase (SGPT) (216.01±4.07 IU/L), blood urea nitrogen (BUN) (22.24±0.31 mg/dl), creatinine (2.13±0.09 mg/dl), β-hydroxybutyric acid (BHBA) (0.46±0.83 mmol/L), and non-esterified fatty acid (NEFA) (1.67±0.71 mmol/L) was significantly higher whereas glucose (30.89±0.38 mg/dl) and calcium (8.10±0.20 mg/dl) levels were significantly decreased in pregnancy toxemic goats as compared to healthy goats.Conclusion:The goats with pregnancy toxemia exhibited clinical signs include anorexia, recumbency, sweetish fruity odor from breath, apparent blindness, bloat, grinding of teeth, and frothy salivation. Biochemically, there were significantly decreased the level of glucose and calcium, and increased level of SGPT, SGOT, BUN, creatinine, BHBA, and NEFA in the pregnancy toxemic goats.

The aim of this study was to evaluate the haemato-biochemical alterations in dogs infected with canine babesiosis presented at the College clinics at Anand, Gujarat. Blood was collected with and without anticoagulant from naturally infected dogs, which were found positive for babesiosis by direct blood smear examination. Statistical analysis of affected (n=24) and healthy (n=8) dogs revealed significant decrease in the mean values of haemoglobin, total leucocyte count, packed cell volume, platelets and lymphocytes and significant increase in the mean values of neutrophils and eosinophils indicating anaemia, thrombocytopaenia, neutrophilia, lymphopenia and eosinophilia in infected dogs as compared to healthy ones. Similarly significant increase in the mean values of serum ALP, ALT, AST, globulin and BUN and decrease in albumin and A:G ratio were observed in infected dogs. The results showed significant alterations in haemato-biochemical attributes in dogs affected with canine babesiosis, and suggested need to rule out possibility of canine babesiosis in all anaemic dogs.